5A3B

Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with ADP-ribose

Summary for 5A3B

Related5A35 5A3A 5A3C
DescriptorSIR2 FAMILY PROTEIN, GLYCINE, ALANINE, ... (7 entities in total)
Functional Keywordstransferase, adp-ribosyltransferase, metalloprotein, nad-dependent, lipoylation, regulatory enzyme, rossmann fold, zinc binding, ros defense
Biological sourceSTREPTOCOCCUS PYOGENES
Total number of polymer chains1
Total molecular weight36082.6
Authors
Primary citation
Rack, J.G.,Morra, R.,Barkauskaite, E.,Kraehenbuehl, R.,Ariza, A.,Qu, Y.,Ortmayer, M.,Leidecker, O.,Cameron, D.R.,Matic, I.,Peleg, A.Y.,Leys, D.,Traven, A.,Ahel, I.
Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59:309-, 2015
PubMed: 26166706 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2015.06.013
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.222301.2%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5a3b
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Molmil generated image of 5a3b
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Molmil generated image of 5a3b
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