5A3A

Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes (Apo form)

Summary for 5A3A

Related5A35 5A3B 5A3C
DescriptorSIR2 FAMILY PROTEIN, GLYCINE, ZINC ION, ... (5 entities in total)
Functional Keywordstransferase, p-ribosyltransferase, metalloprotein, nad-dependent, lipoylation, regulatory enzyme, rossmann fold, zinc binding, ros defense
Biological sourceSTREPTOCOCCUS PYOGENES
Total number of polymer chains1
Total molecular weight36031.8
Authors
Primary citation
Rack, J.G.,Morra, R.,Barkauskaite, E.,Kraehenbuehl, R.,Ariza, A.,Qu, Y.,Ortmayer, M.,Leidecker, O.,Cameron, D.R.,Matic, I.,Peleg, A.Y.,Leys, D.,Traven, A.,Ahel, I.
Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59:309-, 2015
PubMed: 26166706 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2015.06.013
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.54 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213301.6%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5a3a
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Molmil generated image of 5a3a
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Molmil generated image of 5a3a
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