5A3A
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes (Apo form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SIR2 FAMILY PROTEIN | polymer | 303 | 35156.6 | 1 | UniProt (Q1JGN6) | STREPTOCOCCUS PYOGENES | ADP-RIBOSYLATING SIRTUIN, SIRTM |
| 2 | B, C, D, E, F (A) | GLYCINE | non-polymer | 75.1 | 5 | Chemie (GLY) | |||
| 3 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | H, I, J, K, L... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 5 | O (A) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A: 1 - 293 (UniProt: Q1JGN6)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | expression tag |
| Gly -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35156.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 875.2 | |
| All* | Total formula weight | 36031.8 |
