5CIX
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![BU of 5cix by Molmil](/molmil-images/mine/5cix) | Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution | 分子名称: | 2,2',2''-NITRILOTRIETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... | 著者 | Singh, P.K, Pandey, S, Tyagi, T.K, Singh, A, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2015-07-13 | 公開日 | 2015-08-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution. To Be Published
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8UNF
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![BU of 8unf by Molmil](/molmil-images/mine/8unf) | Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ... | 著者 | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | 登録日 | 2023-10-18 | 公開日 | 2023-12-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
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5C50
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2BMD
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1P6N
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![BU of 1p6n by Molmil](/molmil-images/mine/1p6n) | Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-(4R)-amino-L-proline amide bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | 著者 | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2003-04-29 | 公開日 | 2004-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11, 2004
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8V4G
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![BU of 8v4g by Molmil](/molmil-images/mine/8v4g) | X-ray structure of the NADP-dependent reductase from Campylobacter jejuni responsible for the synthesis of CDP-glucitol in the presence of CDP and NADP | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... | 著者 | Schumann, M.E, Thoden, J.B, Holden, H.M, Raushel, F.M. | 登録日 | 2023-11-29 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biosynthesis of Cytidine Diphosphate-6-d-Glucitol for the Capsular Polysaccharides of Campylobacter jejuni. Biochemistry, 63, 2024
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4MNM
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![BU of 4mnm by Molmil](/molmil-images/mine/4mnm) | Crystal Structure of GH18 Chitinase (G77W/E119Q mutant) from Cycas revoluta in complex with (GlcNAc)4 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase A, ... | 著者 | Umemoto, N, Numata, T, Ohnuma, T, Osawa, T, Taira, T, Fukamizo, T. | 登録日 | 2013-09-11 | 公開日 | 2014-09-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of GH18 Chitinase from Cycad, Cycas revoluta To be Published
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5FJK
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![BU of 5fjk by Molmil](/molmil-images/mine/5fjk) | Crystal structure of human JMJD2C catalytic domain in complex 6-ethyl- 5-methyl-7-oxo-4,7-dihydropyrazolo(1,5-a)pyrimidine-3-carbonitrile | 分子名称: | 1,2-ETHANEDIOL, 6-ethyl-5-methyl-7-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile, CHLORIDE ION, ... | 著者 | Cecatiello, V, Pasqualato, S. | 登録日 | 2015-10-09 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Crystal Structures of Human Jmjd2C Catalytic Domain Bound to Inhibitors To be Published
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3CHD
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5FWE
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![BU of 5fwe by Molmil](/molmil-images/mine/5fwe) | JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE | 分子名称: | CHLORIDE ION, GLYCEROL, LYSINE-SPECIFIC DEMETHYLASE 4A, ... | 著者 | Chowdhury, R, Walport, L.J, Schofield, C.J. | 登録日 | 2016-02-15 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases. Nat.Commun., 7, 2016
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2BHK
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![BU of 2bhk by Molmil](/molmil-images/mine/2bhk) | Crystal structure of human growth and differentiation factor 5 (GDF5) | 分子名称: | GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL | 著者 | Schreuder, H, Liesum, A, Pohl, J, Kruse, M, Koyama, M. | 登録日 | 2005-01-12 | 公開日 | 2005-03-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites. Biochem.Biophys.Res.Commun., 329, 2005
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2BX8
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![BU of 2bx8 by Molmil](/molmil-images/mine/2bx8) | Human serum albumin complexed with azapropazone | 分子名称: | AZAPROPAZONE, SERUM ALBUMIN | 著者 | Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Curry, S. | 登録日 | 2005-07-25 | 公開日 | 2005-09-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. J.Mol.Biol., 353, 2005
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1OS7
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![BU of 1os7 by Molmil](/molmil-images/mine/1os7) | Crystal structure of TauD with iron, alpha-ketoglutarate and Taurine bound at pH 7.5 | 分子名称: | 2-AMINOETHANESULFONIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent taurine dioxygenase, ... | 著者 | O'Brien, J.R, Schuller, D.J, Yang, V.S, Dillard, B.D, Lanzilotta, W.N. | 登録日 | 2003-03-18 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Substrate-Induced Conformational Changes in Escherichia coli Taurine/alpha-Ketoglutarate Dioxygenase and Insight Into the Oligomeric Structure Biochemistry, 42, 2003
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7QBP
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![BU of 7qbp by Molmil](/molmil-images/mine/7qbp) | Crystal structure of R2-like ligand-binding oxidase from Saccharopolyspora Erythraea | 分子名称: | FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ... | 著者 | Srinivas, V, Diamanti, R, Lebrette, H, Hogbom, M. | 登録日 | 2021-11-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase. Febs Lett., 596, 2022
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7QCO
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![BU of 7qco by Molmil](/molmil-images/mine/7qco) | The structure of Photosystem I tetramer from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, CHLOROPHYLL A, ... | 著者 | Semchonok, D.A, Mondal, J, Cooper, J.C, Schlum, K, Li, M, Amin, M, Sorzano, C.O.S, Ramirez-Aportela, E, Kastritis, P.L, Boekema, E.J, Guskov, A, Bruce, B.D. | 登録日 | 2021-11-24 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structure of a tetrameric photosystem I from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium. Plant Commun., 3, 2022
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5FOI
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![BU of 5foi by Molmil](/molmil-images/mine/5foi) | Crystal structure of mycinamicin VIII C21 methyl hydroxylase MycCI from Micromonospora griseorubida bound to mycinamicin VIII | 分子名称: | GLYCEROL, MYCINAMICIN VIII C21 METHYL HYDROXYLASE, Mycinamicin VIII, ... | 著者 | Demars, M, Sheng, F, Podust, L.M, Sherman, D.H. | 登録日 | 2015-11-22 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Biochemical and Structural Characterization of Mycci, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway. Acs Chem.Biol., 11, 2016
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4MTK
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5C8M
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![BU of 5c8m by Molmil](/molmil-images/mine/5c8m) | EGFR kinase domain mutant "TMLR" with compound 17 | 分子名称: | 2-methyl-N-{2-[4-(methylsulfonyl)piperidin-1-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine, Epidermal growth factor receptor | 著者 | Eigenbrot, C, Yu, C. | 登録日 | 2015-06-25 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. J.Med.Chem., 58, 2015
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4MJK
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5FZA
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![BU of 5fza by Molmil](/molmil-images/mine/5fza) | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment 2-piperidin-4-yloxy-5-(trifluoromethyl)pyridine (N10072a) (ligand modelled based on PANDDA event map) | 分子名称: | 1,2-ETHANEDIOL, 2-piperidin-4-yloxy-5-(trifluoromethyl)pyridine, CHLORIDE ION, ... | 著者 | Nowak, R, Krojer, T, Pearce, N, Johansson, C, Gileadi, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, von Delft, F, Brennan, P.E, Oppermann, U. | 登録日 | 2016-03-12 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with 3D Fragment 2-Piperidin-4-Yloxy-5-(Trifluoromethyl)Pyridine (N10072A) (Ligand Modelled Based on Pandda Event Map) To be Published
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7QGQ
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8UJY
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![BU of 8ujy by Molmil](/molmil-images/mine/8ujy) | Crystal structure of human WD repeat-containing protein 5 in complex with 4-(3,5-dimethoxybenzyl)-9-(4-fluoro-2-methylphenyl)-7-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (compound 8) | 分子名称: | (9P)-4-[(3,5-dimethoxyphenyl)methyl]-9-(4-fluoro-2-methylphenyl)-7-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-3,4-dihydro-1,4-benzoxazepin-5(2H)-one, WD repeat-containing protein 5 | 著者 | Zhao, B, Amporndanai, K, Fesik, S.W. | 登録日 | 2023-10-11 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J.Med.Chem., 66, 2023
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2WOQ
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![BU of 2woq by Molmil](/molmil-images/mine/2woq) | Porphobilinogen Synthase (HemB) in Complex with 5-acetamido-4- oxohexanoic acid (Alaremycin 2) | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALAREMYCIN 2, ... | 著者 | Heinemann, I.U, Schulz, C, Schubert, W.-D, Heinz, D.W, Wang, Y.-G, Kobayashi, Y, Awa, Y, Wachi, M, Jahn, D, Jahn, M. | 登録日 | 2009-07-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin. Antimicrob. Agents Chemother., 54, 2010
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4MKK
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![BU of 4mkk by Molmil](/molmil-images/mine/4mkk) | Crystal structure of C115A mutant L-methionine gamma-lyase from Citrobacter freundii modified by allicine | 分子名称: | CHLORIDE ION, Methionine gamma-lyase, POTASSIUM ION, ... | 著者 | Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V. | 登録日 | 2013-09-05 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme. Acta Crystallogr.,Sect.D, 70, 2014
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5FYY
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![BU of 5fyy by Molmil](/molmil-images/mine/5fyy) | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment 3-pyridin-3-ylaniline (N05798a) (ligand modelled based on PANDDA event map) | 分子名称: | 1,2-ETHANEDIOL, 3-(pyridin-3-yl)aniline, CHLORIDE ION, ... | 著者 | Nowak, R, Krojer, T, Johansson, C, Gileadi, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, Pearce, N, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, von Delft, F, Brennan, P.E, Oppermann, U. | 登録日 | 2016-03-10 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with N05798A To be Published
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