5FJK

Crystal structure of human JMJD2C catalytic domain in complex 6-ethyl- 5-methyl-7-oxo-4,7-dihydropyrazolo(1,5-a)pyrimidine-3-carbonitrile

Summary for 5FJK

• Entry DOI: 10.2210/pdb5fjk/pdb
• Related: 5FJH
• Descriptor: LYSINE-SPECIFIC DEMETHYLASE 4C, ZINC ION, NICKEL (II) ION, ... (7 entities in total)
• Functional Keywords: oxidoreductase, transcription regulation, metal binding, demethylase, lysine-specific demethylase 4c
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : Q9H3R0
• Total number of polymer chains: 1
• Total formula weight: 41295.71

Authors

Cecatiello, V.,Pasqualato, S. (deposition date: 2015-10-09, release date: 2015-10-21, Last modification date: 2024-01-10)

• Primary citation: Cecatiello, V.,Pasqualato, S.; Crystal Structures of Human Jmjd2C Catalytic Domain Bound to Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.66 Å)