8V4G

X-ray structure of the NADP-dependent reductase from Campylobacter jejuni responsible for the synthesis of CDP-glucitol in the presence of CDP and NADP

Summary for 8V4G

Entry DOI	10.2210/pdb8v4g/pdb
Descriptor	Putative nucleotide sugar dehydratase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	capsular polysaccharide, short chain dehydrogenase, oxidoreductase
Biological source	Campylobacter jejuni
Total number of polymer chains	2
Total formula weight	80242.11
Authors	Schumann, M.E.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. (deposition date: 2023-11-29, release date: 2023-12-20, Last modification date: 2024-03-13)
Primary citation	Ghosh, M.K.,Narindoshvili, T.,Thoden, J.B.,Schumann, M.E.,Holden, H.M.,Raushel, F.M. Biosynthesis of Cytidine Diphosphate-6-d-Glucitol for the Capsular Polysaccharides of Campylobacter jejuni. Biochemistry, 63:699-710, 2024 Cited by PubMed: 38386885 DOI: 10.1021/acs.biochem.3c00706 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation