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1L7A
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structural Genomics, crystal structure of Cephalosporin C deacetylase
分子名称: Cephalosporin C deacetylase
著者Zhang, R, Koroleva, O, Collert, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2002-03-14
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献1.5A crystal structure of the Cephalosporin C deacetylase
To be Published
4TR7
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Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis
分子名称: DNA polymerase III subunit beta
著者Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
登録日2014-06-14
公開日2014-09-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
1LDM
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Refined crystal structure of dogfish M4 apo-lactate dehydrogenase
分子名称: M4 LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID
著者Griffith, J.P, Rossmann, M.G.
登録日1987-11-25
公開日1989-07-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined crystal structure of dogfish M4 apo-lactate dehydrogenase.
J.Mol.Biol., 198, 1987
1L83
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A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE
分子名称: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Eriksson, A.E, Matthews, B.W.
登録日1992-01-21
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene.
Nature, 355, 1992
4TM3
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Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-Br
分子名称: BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, KtzI
著者Setser, J.W, Drennan, C.L.
登録日2014-05-30
公開日2014-09-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase.
Biochemistry, 53, 2014
3KXT
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Crystal structure of Sulfolobus Cren7-dsDNA complex
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', Chromatin protein Cren7
著者Feng, Y, Wang, J.
登録日2009-12-03
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex
Protein Sci., 19, 2010
1GOO
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Thermostable xylanase I from Thermoascus aurantiacus - Cryocooled glycerol complex
分子名称: ENDO-1,4-BETA-XYLANASE, GLYCEROL
著者Eckert, K, Andrei, C, Larsen, S, Lo Leggio, L.
登録日2001-10-22
公開日2001-12-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Substrate Specificity and Subsite Mobility in T. Aurantiacus Xylanase 10A
FEBS Lett., 509, 2001
7Y8F
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Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30o and GRIP Peptide
分子名称: DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ...
著者Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T.
登録日2022-06-23
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Eur.J.Med.Chem., 253, 2023
1GRA
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SUBSTRATE BINDING AND CATALYSIS BY GLUTATHIONE REDUCTASE AS DERIVED FROM REFINED ENZYME: SUBSTRATE CRYSTAL STRUCTURES AT 2 ANGSTROMS RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ...
著者Karplus, P.A, Schulz, G.E.
登録日1992-12-15
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 A resolution.
J.Mol.Biol., 210, 1989
5D9D
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Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ...
著者Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T.
登録日2015-08-18
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography.
Sci Rep, 5, 2015
1H2H
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Crystal structure of TM1643
分子名称: HYPOTHETICAL PROTEIN TM1643, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Yang, Z, Savchenko, A, Edwards, A, Arrowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2002-08-08
公開日2002-08-15
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
J. Biol. Chem., 278, 2003
7Y6J
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Crystal structure of human transthyretin variant A97S at pH 5.4
分子名称: GLYCEROL, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-20
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7Y8G
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Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30a and GRIP Peptide
分子名称: DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ...
著者Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T.
登録日2022-06-23
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Eur.J.Med.Chem., 253, 2023
1XJL
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Structure of human annexin A2 in the presence of calcium ions
分子名称: Annexin A2, CALCIUM ION
著者Rosengarth, A, Luecke, H.
登録日2004-09-23
公開日2004-11-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein?
Annexins, 1, 2004
1XJX
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The crystal structures of the DNA binding sites of the RUNX1 transcription factor
分子名称: 5'-D(*TP*CP*TP*GP*CP*GP*GP*TP*C)-3', 5'-D(*TP*GP*AP*CP*CP*GP*CP*AP*G)-3'
著者Kitayner, M, Rozenberg, H, Rabinovich, D, Shakked, Z.
登録日2004-09-26
公開日2005-03-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the DNA-binding site of Runt-domain transcription regulators.
Acta Crystallogr.,Sect.D, 61, 2005
1HL3
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CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide
分子名称: C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE
著者Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M.
登録日2003-03-13
公開日2003-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission
Embo J., 22, 2003
1FXV
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PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE
分子名称: CALCIUM ION, PENICILLIN ACYLASE, PENICILLIN G
著者Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B.
登録日2000-09-27
公開日2001-03-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
1XKW
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Pyochelin outer membrane receptor FptA from Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, Fe(III)-pyochelin receptor, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者Cobessi, D, Celia, H, Pattus, F.
登録日2004-09-30
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa
J.Mol.Biol., 352, 2005
7YBR
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Crystal structure of human transthyretin variant A97S complexed with Tolcapone
分子名称: Tolcapone, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-29
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YCQ
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Crystal structure of human transthyretin variant A97S complexed with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-07-01
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
1FZ3
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METHANE MONOOXYGENASE HYDROXYLASE, FORM III SOAK AT PH 6.2 (0.1 M PIPES)
分子名称: CALCIUM ION, FE (III) ION, FORMIC ACID, ...
著者Whittington, D.A, Lippard, S.J.
登録日2000-10-03
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site.
J.Am.Chem.Soc., 123, 2001
1FWE
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT WITH ACETOHYDROXAMIC ACID (AHA) BOUND
分子名称: ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE
著者Pearson, M.A, Karplus, P.A.
登録日1997-04-23
公開日1997-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
4G04
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High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
分子名称: Serum albumin
著者Cao, H.L, Yin, D.C.
登録日2012-07-09
公開日2013-07-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
To be Published
2ZO2
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Mouse NP95 SRA domain non-specific DNA complex
分子名称: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION
著者Hashimoto, H, Horton, J.R, Cheng, X.
登録日2008-05-05
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
1FWD
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 9.4
分子名称: NICKEL (II) ION, UREASE
著者Pearson, M.A, Karplus, P.A.
登録日1997-04-23
公開日1997-10-15
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997

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