PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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3DCU	FXR with SRC1 and GSK8062 分子名称: 6-(4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)naphthalene-1-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1 著者 Williams, S.P, Madauss, K.P. 登録日 2008-06-04 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064. Bioorg.Med.Chem.Lett., 18, 2008
3DJK	Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-0255A 分子名称: (5R)-1,3-dioxepan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, Protease, ... 著者 Wang, Y.F, Weber, I.T. 登録日 2008-06-23 公開日 2008-09-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies J.Med.Chem., 51, 2008
6P1B	Transcription antitermination factor Q21 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Q protein 著者 Yin, Z, Ebright, R.H. 登録日 2019-05-19 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.942 Å) 主引用文献 Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
4DWL	Avd molecule from Bordetella bacteriophage DGR 分子名称: Bbp7, PHOSPHATE ION 著者 Ghosh, P, Al-Ayyoubi, M. 登録日 2012-02-24 公開日 2013-02-27 最終更新日 2015-01-14 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structure of the essential diversity-generating retroelement protein bAvd and its functionally important interaction with reverse transcriptase. Structure, 21, 2013
1DDL	DESMODIUM YELLOW MOTTLE TYMOVIRUS 分子名称: DESMODIUM YELLOW MOTTLE VIRUS, RNA (5'-R(P*UP*U)-3'), RNA (5'-R(P*UP*UP*UP*UP*UP*UP*U)-3') 著者 Larson, S.B, Day, J, Canady, M.A, Greenwood, A, McPherson, A. 登録日 1999-11-10 公開日 2000-10-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Refined structure of desmodium yellow mottle tymovirus at 2.7 A resolution. J.Mol.Biol., 301, 2000
4DZR	The crystal structure of protein-(glutamine-N5) methyltransferase (release factor-specific) from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Tan, K, Chhor, G, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-03-01 公開日 2012-03-14 実験手法 X-RAY DIFFRACTION (2.551 Å) 主引用文献 The crystal structure of protein-(glutamine-N5) methyltransferase (release factor-specific) from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 To be Published
3T0M	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: (2-{2-[(2,5-dimethoxyphenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Thiel, P, Ottmann, C. 登録日 2011-07-20 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
4DDH	Pantothenate synthetase in complex with 6-methoxy-1-benzofuran-3-yl acetic acid 分子名称: (6-methoxy-1-benzofuran-3-yl)acetic acid, 1,2-ETHANEDIOL, ETHANOL, ... 著者 Silvestre, H.L. 登録日 2012-01-18 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
3SQJ	Recombinant human serum albumin from transgenic plant 分子名称: MYRISTIC ACID, Serum albumin 著者 He, Y, Yang, D. 登録日 2011-07-05 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Large-scale production of functional human serum albumin from transgenic rice seeds. Proc.Natl.Acad.Sci.USA, 108, 2011
3SOU	Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION 著者 Rajakumara, E, Patel, D.J. 登録日 2011-06-30 公開日 2011-08-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8001 Å) 主引用文献 PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011
4DK7	Crystal structure of LXR ligand binding domain in complex with full agonist 1 分子名称: ACETATE ION, CALCIUM ION, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylbenzenesulfonamide, ... 著者 Piper, D.E, Xu, H. 登録日 2012-02-03 公開日 2012-03-21 最終更新日 2012-05-09 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of a new binding mode for a series of liver X receptor agonists. Bioorg.Med.Chem.Lett., 22, 2012
3SRD	Human M2 pyruvate kinase in complex with fructose 1-6 bisphosphate and Oxalate. 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... 著者 Morgan, H.P, O'Reilly, F, Palmer, R, McNae, I.W, Nowicki, M.W, Wear, M.A, Fothergill-Gilmore, L.A, Walkinshaw, M.D. 登録日 2011-07-07 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Allosetric regulation of M2 pyruvate kinase. To be Published
3T6J	Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 3.0 Angstroms 分子名称: Dipeptidyl peptidase 3, Tynorphin 著者 Bezerra, G.A, Gruber, K. 登録日 2011-07-28 公開日 2012-04-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.976 Å) 主引用文献 Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc.Natl.Acad.Sci.USA, 109, 2012
3T6R	Structure of UHRF1 in complex with unmodified H3 N-terminal tail 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3.1t N-terminal peptide, MAGNESIUM ION, ... 著者 Xie, S, Jakoncic, J, Qian, C.M. 登録日 2011-07-29 公開日 2011-11-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail J.Mol.Biol., 415, 2012
4DHP	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3SOW	Structure of UHRF1 PHD finger in complex with histone H3K4me3 1-9 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION 著者 Rajakumara, E, Patel, D.J. 登録日 2011-06-30 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9501 Å) 主引用文献 PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011
3SP5	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol 分子名称: 14-3-3 protein sigma, Cotylenol, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-01 公開日 2016-05-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem.Biol., 20, 2013
3SPR	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer FC-THF 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A-THF, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-03 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SS7	Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.55 A resolution 分子名称: D-serine dehydratase, GLYCEROL, POTASSIUM ION, ... 著者 Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. 登録日 2011-07-07 公開日 2012-01-18 最終更新日 2012-02-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of D-serine dehydratase from Escherichia coli. Biochim.Biophys.Acta, 1824, 2011
4DZ1	Crystal structure of DalS, an ATP binding cassette transporter for D-alanine from Salmonella enterica 分子名称: D-ALANINE, DalS D-Alanine transporter 著者 Mok, M, Junop, M. 登録日 2012-02-29 公開日 2012-03-21 最終更新日 2012-05-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of DalS, an ATP-binding Cassette Transporter for D-Alanine, and Its Role in Pathogenesis in Salmonella enterica. J.Biol.Chem., 287, 2012
4E2T	Crystal Structures of RadA intein from Pyrococcus horikoshii 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Pho radA intein 著者 Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H. 登録日 2012-03-09 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein. J.Mol.Biol., 421, 2012
4E05	Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... 著者 Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. 登録日 2012-03-02 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3Y	X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Lashkov, A.A, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. 登録日 2012-03-11 公開日 2013-05-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution To be Published
4E06	Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... 著者 Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. 登録日 2012-03-02 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.196 Å) 主引用文献 Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
3SRK	A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase 分子名称: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, POTASSIUM ION, Pyruvate kinase, ... 著者 Morgan, H.P, Walsh, M, Blackburn, E.A, Wear, M.A, Boxer, M, Shen, M, McNae, I.W, Michels, P.A.M, Auld, D.S, Fothergill-Gilmore, L.A, Walkinshaw, M.D. 登録日 2011-07-07 公開日 2012-07-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase To be Published

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