PDB: 2824 件ウェブページステータス検索Chemie searchBIRD

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6EWI	Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant 分子名称: Centrosomal protein 120 著者 van Breugel, M. 登録日 2017-11-04 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
6EWP	Mus musculus CEP120 third C2 domain (C2C) 分子名称: Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL 著者 van Breugel, M, al-Jassar, C. 登録日 2017-11-06 公開日 2018-05-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
2J3D	Native monoclinic form of Torpedo acetylcholinesterase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, MAGNESIUM ION 著者 Harel, M, Sussman, J.L. 登録日 2006-08-20 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Native Monoclinic Form of Torpedo Acetylcholinesterase To be Published
2C9K	Structure of the functional form of the mosquito-larvicidal Cry4Aa toxin from Bacillus thuringiensis at 2.8 A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PESTICIDAL CRYSTAL PROTEIN CRY4AA 著者 Boonserm, P, Mo, M, Angsuthanasombat, C, Lescar, J. 登録日 2005-12-13 公開日 2006-04-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the Functional Form of the Mosquito Larvicidal Cry4Aa Toxin from Bacillus Thuringiensis at 2.8-Angstrom Resolution. J.Bacteriol., 188, 2006
6AZE	Crystal Structure of the BPTF PHD-bromodomain module bound to H3KC4me3 methyl lysine analog 分子名称: ALA-ARG-THR-ML3-GLN-THR, Nucleosome-remodeling factor subunit BPTF, ZINC ION 著者 Chen, Z, Ruthenburg, A.J. 登録日 2017-09-11 公開日 2018-09-19 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.451 Å) 主引用文献 Quantitative and structural assessment of methyllysine analog engagement by cognate binding proteins reveals decrements that can impact qualitative experiment interpretation To be published
6EXN	Post-catalytic P complex spliceosome with 3' splice site docked 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... 著者 Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. 登録日 2017-11-08 公開日 2018-01-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science, 358, 2017
6EWH	Oreochromis niloticus CEP120 second C2 domain (C2B) G307S mutant 分子名称: Centrosomal protein 120 著者 van Breugel, M, al-Jassar, C, Yu, M. 登録日 2017-11-04 公開日 2018-05-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
6EWL	Danio rerio CEP120 first C2 domain (C2A) 分子名称: Centrosomal protein 120 著者 van Breugel, M, al-Jassar, C. 登録日 2017-11-04 公開日 2018-05-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
8I0V	The cryo-EM structure of human post-Bact complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0P	The cryo-EM structure of human pre-Bact complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0W	The cryo-EM structure of human C complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0R	The cryo-EM structure of human Bact-I complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0U	The cryo-EM structure of human Bact-IV complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0T	The cryo-EM structure of human Bact-III complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0S	The cryo-EM structure of human Bact-II complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
4JJE	Caspase-3 specific unnatural amino acid peptides 分子名称: Caspase inhibitor, Caspase-3 著者 Vickers, C.J, Gonzalez-Paez, G.E, Wolan, D.W. 登録日 2013-03-07 公開日 2013-06-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.481 Å) 主引用文献 Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. Acs Chem.Biol., 8, 2013
6C0T	Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain bound with N46 分子名称: DIMETHYL SULFOXIDE, N-[(3R,4R)-4-{[4-(2-fluoro-3-methoxy-6-propoxybenzene-1-carbonyl)benzene-1-carbonyl]amino}pyrrolidin-3-yl]-1H-indazole-5-carboxamide, TRIETHYLENE GLYCOL, ... 著者 Qin, L, Sankaran, B, Kim, C. 登録日 2018-01-02 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural basis for selective inhibition of human PKG I alpha by the balanol-like compound N46. J. Biol. Chem., 293, 2018
6F1U	N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... 著者 Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. 登録日 2017-11-23 公開日 2018-01-17 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
6F38	Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... 著者 Lau, C.K, Urnavicius, L, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. 登録日 2017-11-28 公開日 2018-01-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
2J3Q	Torpedo acetylcholinesterase complexed with fluorophore thioflavin T 分子名称: 2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... 著者 Harel, M, Cusack, B, Johnson, J.L, Silman, I, Sussman, J.L, Rosenberry, T.L. 登録日 2006-08-23 公開日 2007-09-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site. J. Am. Chem. Soc., 130, 2008
5N5J	Human MMP12 in complex with 3-(5-(1,2-dithiolan-3-yl)pentanamido)propane-1-sulfonate 分子名称: 3-[5-[(3~{S})-1,2-dithiolan-3-yl]pentanoylamino]propane-1-sulfonic acid, ACETOHYDROXAMIC ACID, CALCIUM ION, ... 著者 Calderone, V. 登録日 2017-02-14 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX). J. Med. Chem., 60, 2017
6BN8	Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET55 PROTAC. 分子名称: Bromodomain-containing protein 4, DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, ... 著者 Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S. 登録日 2017-11-16 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.990035 Å) 主引用文献 Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat. Chem. Biol., 14, 2018
1YHJ	Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives 分子名称: (2R)-2-{[6-(BENZYLOXY)-9-ISOPROPYL-9H-PURIN-2-YL]AMINO}BUTAN-1-OL, Pyridoxal Kinase 著者 Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. 登録日 2005-01-09 公開日 2005-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. J.Biol.Chem., 280, 2005
6F1Z	Roadblock-1 region of the dynein tail/dynactin/BICDR1 complex 分子名称: Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain roadblock-type 1 著者 Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. 登録日 2017-11-23 公開日 2018-01-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
1LVG	Crystal structure of mouse guanylate kinase in complex with GMP and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, ... 著者 Sekulic, N, Shuvalova, L, Spangenberg, O, Konrad, M, Lavie, A. 登録日 2002-05-28 公開日 2002-12-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural characterization of the closed conformation of mouse guanylate kinase. J.Biol.Chem., 277, 2002

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