Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3SMB
DownloadVisualize
BU of 3smb by Molmil
Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF)
分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ...
著者Crichlow, G.V, Lolis, E.J.
登録日2011-06-27
公開日2012-10-03
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates.
Biochemistry, 51, 2012
3SME
DownloadVisualize
BU of 3sme by Molmil
Structure of PTP1B inactivated by H2O2/bicarbonate
分子名称: MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1
著者Tanner, J.J, Singh, H.
登録日2011-06-27
公開日2011-10-19
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases.
J.Am.Chem.Soc., 133, 2011
3SMZ
DownloadVisualize
BU of 3smz by Molmil
Human raver1 RRM1-3 domains (residues 39-320)
分子名称: Ribonucleoprotein PTB-binding 1, SULFATE ION
著者Rangarajan, E.S, Lee, J.H, Izard, T.
登録日2011-06-28
公開日2011-08-10
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Apo raver1 structure reveals distinct RRM domain orientations.
Protein Sci., 20, 2011
3SK9
DownloadVisualize
BU of 3sk9 by Molmil
Crystal structure of the Thermus thermophilus cas3 HD domain
分子名称: Putative uncharacterized protein TTHB187
著者Bailey, S, Mulepati, S.
登録日2011-06-22
公開日2011-07-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3).
J.Biol.Chem., 286, 2011
3SNO
DownloadVisualize
BU of 3sno by Molmil
Crystal structure of a putative aminotransferase (NCgl2491) from Corynebacterium glutamicum ATCC 13032 at 1.60 A resolution
分子名称: 1,2-ETHANEDIOL, Hypothetical aminotransferase
著者Joint Center for Structural Genomics (JCSG)
登録日2011-06-29
公開日2011-07-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a Hypothetical aminotransferase (NCgl2491) from CORYNEBACTERIUM GLUTAMICUM ATCC 13032 KITASATO at 1.60 A resolution
To be published
3SO6
DownloadVisualize
BU of 3so6 by Molmil
Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain
分子名称: LDL receptor adaptor protein, Low-density lipoprotein receptor
著者Dvir, H, Zajonc, D.M.
登録日2011-06-29
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail.
Proc.Natl.Acad.Sci.USA, 109, 2012
3S9T
DownloadVisualize
BU of 3s9t by Molmil
Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ...
著者Grazulis, S, Manakova, E, Tamulaitiene, G.
登録日2011-06-02
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.
Eur.J.Med.Chem., 51, 2012
3SA2
DownloadVisualize
BU of 3sa2 by Molmil
Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1014
分子名称: 6-ethyl-5-[3-(5-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Anderson, A.C, Beierlein, J.M.
登録日2011-06-02
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献SAR studies of heterocyclic propargyl-linked TMP analogs to Bacillus dihydrofolate reductase
to be published
3SAA
DownloadVisualize
BU of 3saa by Molmil
Crystal structure of Wild-type HIV-1 protease in complex With AF77
分子名称: N-[(2S,3R)-4-{(cyclohexylmethyl)[(4-methoxyphenyl)sulfonyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-3-hydroxybenzamide, PHOSPHATE ION, Protease
著者Schiffer, C.A, Nalam, M.N.L.
登録日2011-06-02
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance
To be Published
3SB6
DownloadVisualize
BU of 3sb6 by Molmil
Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization
分子名称: CHLORIDE ION, COPPER (II) ION, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3S92
DownloadVisualize
BU of 3s92 by Molmil
Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
分子名称: (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 3
著者Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC)
登録日2011-05-31
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
3SB4
DownloadVisualize
BU of 3sb4 by Molmil
Crystal structure of a leucine-rich repeat protein (BT_1240) from Bacteroides thetaiotaomicron VPI-5482 at 1.99 A resolution
分子名称: GLYCEROL, Hypothetical leucine rich repeat protein, TETRAETHYLENE GLYCOL
著者Joint Center for Structural Genomics (JCSG)
登録日2011-06-03
公開日2011-06-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of a Hypothetical leucine rich repeat protein (BT_1240) from Bacteroides thetaiotaomicron VPI-5482 at 1.99 A resolution
To be published
3SEO
DownloadVisualize
BU of 3seo by Molmil
Crystal structure of VopL C terminal domain
分子名称: CHLORIDE ION, VopL C terminal domain protein
著者Yu, B, Rosen, M.K, Tomchick, D.R.
登録日2011-06-10
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献Mechanism of actin filament nucleation by the bacterial effector VopL.
Nat.Struct.Mol.Biol., 18, 2011
3SGP
DownloadVisualize
BU of 3sgp by Molmil
Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4016 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGW
DownloadVisualize
BU of 3sgw by Molmil
Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MALONIC ACID, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-06-15
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis.
Bmc Struct.Biol., 11, 2011
3SHL
DownloadVisualize
BU of 3shl by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V74KL25A at cryogenic temperature
分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
著者Caro, J.A, Sue, G, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B.
登録日2011-06-16
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Redirection of internal ionizable residues by engineered cavities
To be Published
3SKD
DownloadVisualize
BU of 3skd by Molmil
Crystal structure of the Thermus thermophilus cas3 HD domain in the presence of Ni2+
分子名称: NICKEL (II) ION, Putative uncharacterized protein TTHB187
著者Bailey, S, Mulepati, S.
登録日2011-06-22
公開日2011-07-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3).
J.Biol.Chem., 286, 2011
3SJV
DownloadVisualize
BU of 3sjv by Molmil
Crystal structure of the RL42 TCR in complex with HLA-B8-FLR
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J.
登録日2011-06-22
公開日2012-02-29
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
7N55
DownloadVisualize
BU of 7n55 by Molmil
The crystal structure of the mutant I38T PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514
分子名称: 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ...
著者Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W.
登録日2021-06-04
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Eur.J.Med.Chem., 247, 2023
7N8F
DownloadVisualize
BU of 7n8f by Molmil
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988288
分子名称: Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W.
登録日2021-06-14
公開日2022-06-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Eur.J.Med.Chem., 247, 2023
3JYF
DownloadVisualize
BU of 3jyf by Molmil
The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
分子名称: 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Fan, Y, Volkart, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-09-21
公開日2009-09-29
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
To be Published
7N18
DownloadVisualize
BU of 7n18 by Molmil
Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by a Chiral Hydroxamic Acid
分子名称: (3R)-3-(4-chlorophenyl)-N,5-dihydroxypentanamide, (3S)-3-(4-chlorophenyl)-N,5-dihydroxypentanamide, Botulinum neurotoxin type A, ...
著者Silvaggi, N.R, Allen, K.N.
登録日2021-05-27
公開日2022-07-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease.
Acs Med.Chem.Lett., 12, 2021
7MQK
DownloadVisualize
BU of 7mqk by Molmil
AAC(3)-IIIa in complex with CoA and sisomicin
分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside N(3)-acetyltransferase III, COENZYME A, ...
著者Zielinski, M, Berghuis, A.M.
登録日2021-05-05
公開日2022-07-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa.
Plos One, 17, 2022
7MQL
DownloadVisualize
BU of 7mql by Molmil
AAC(3)-IIIa in complex with CoA and neomycin
分子名称: Aminoglycoside N(3)-acetyltransferase III, COENZYME A, FORMIC ACID, ...
著者Zielinski, M, Berghuis, A.M.
登録日2021-05-05
公開日2022-07-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa.
Plos One, 17, 2022
7MXO
DownloadVisualize
BU of 7mxo by Molmil
CryoEM structure of human NKCC1
分子名称: CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2021-05-19
公開日2022-09-28
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon