PDB: 238582 件ウェブページステータス検索Chemie searchBIRD

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3SMB	Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF) 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ... 著者 Crichlow, G.V, Lolis, E.J. 登録日 2011-06-27 公開日 2012-10-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates. Biochemistry, 51, 2012
3SME	Structure of PTP1B inactivated by H2O2/bicarbonate 分子名称: MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 著者 Tanner, J.J, Singh, H. 登録日 2011-06-27 公開日 2011-10-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases. J.Am.Chem.Soc., 133, 2011
3SMZ	Human raver1 RRM1-3 domains (residues 39-320) 分子名称: Ribonucleoprotein PTB-binding 1, SULFATE ION 著者 Rangarajan, E.S, Lee, J.H, Izard, T. 登録日 2011-06-28 公開日 2011-08-10 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Apo raver1 structure reveals distinct RRM domain orientations. Protein Sci., 20, 2011
3SK9	Crystal structure of the Thermus thermophilus cas3 HD domain 分子名称: Putative uncharacterized protein TTHB187 著者 Bailey, S, Mulepati, S. 登録日 2011-06-22 公開日 2011-07-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3). J.Biol.Chem., 286, 2011
3SNO	Crystal structure of a putative aminotransferase (NCgl2491) from Corynebacterium glutamicum ATCC 13032 at 1.60 A resolution 分子名称: 1,2-ETHANEDIOL, Hypothetical aminotransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-29 公開日 2011-07-20 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a Hypothetical aminotransferase (NCgl2491) from CORYNEBACTERIUM GLUTAMICUM ATCC 13032 KITASATO at 1.60 A resolution To be published
3SO6	Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain 分子名称: LDL receptor adaptor protein, Low-density lipoprotein receptor 著者 Dvir, H, Zajonc, D.M. 登録日 2011-06-29 公開日 2012-04-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail. Proc.Natl.Acad.Sci.USA, 109, 2012
3S9T	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-02 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SA2	Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1014 分子名称: 6-ethyl-5-[3-(5-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Anderson, A.C, Beierlein, J.M. 登録日 2011-06-02 公開日 2012-06-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 SAR studies of heterocyclic propargyl-linked TMP analogs to Bacillus dihydrofolate reductase to be published
3SAA	Crystal structure of Wild-type HIV-1 protease in complex With AF77 分子名称: N-[(2S,3R)-4-{(cyclohexylmethyl)[(4-methoxyphenyl)sulfonyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-3-hydroxybenzamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SB6	Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization 分子名称: CHLORIDE ION, COPPER (II) ION, Lysozyme 著者 Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. 登録日 2011-06-03 公開日 2011-09-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
3S92	Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 分子名称: (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 3 著者 Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-05-31 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 To be Published
3SB4	Crystal structure of a leucine-rich repeat protein (BT_1240) from Bacteroides thetaiotaomicron VPI-5482 at 1.99 A resolution 分子名称: GLYCEROL, Hypothetical leucine rich repeat protein, TETRAETHYLENE GLYCOL 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-03 公開日 2011-06-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal structure of a Hypothetical leucine rich repeat protein (BT_1240) from Bacteroides thetaiotaomicron VPI-5482 at 1.99 A resolution To be published
3SEO	Crystal structure of VopL C terminal domain 分子名称: CHLORIDE ION, VopL C terminal domain protein 著者 Yu, B, Rosen, M.K, Tomchick, D.R. 登録日 2011-06-10 公開日 2011-08-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 Mechanism of actin filament nucleation by the bacterial effector VopL. Nat.Struct.Mol.Biol., 18, 2011
3SGP	Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain 著者 Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2011-06-15 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4016 Å) 主引用文献 Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
3SGW	Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MALONIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-06-15 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. Bmc Struct.Biol., 11, 2011
3SHL	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74KL25A at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Sue, G, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2011-06-16 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Redirection of internal ionizable residues by engineered cavities To be Published
3SKD	Crystal structure of the Thermus thermophilus cas3 HD domain in the presence of Ni2+ 分子名称: NICKEL (II) ION, Putative uncharacterized protein TTHB187 著者 Bailey, S, Mulepati, S. 登録日 2011-06-22 公開日 2011-07-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3). J.Biol.Chem., 286, 2011
3SJV	Crystal structure of the RL42 TCR in complex with HLA-B8-FLR 分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... 著者 Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. 登録日 2011-06-22 公開日 2012-02-29 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188, 2012
7N55	The crystal structure of the mutant I38T PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514 分子名称: 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-06-04 公開日 2022-06-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
3JYF	The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 分子名称: 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Fan, Y, Volkart, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-09-21 公開日 2009-09-29 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 To be Published
7N8F	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988288 分子名称: Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-06-14 公開日 2022-06-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
7N18	Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by a Chiral Hydroxamic Acid 分子名称: (3R)-3-(4-chlorophenyl)-N,5-dihydroxypentanamide, (3S)-3-(4-chlorophenyl)-N,5-dihydroxypentanamide, Botulinum neurotoxin type A, ... 著者 Silvaggi, N.R, Allen, K.N. 登録日 2021-05-27 公開日 2022-07-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. Acs Med.Chem.Lett., 12, 2021
7MQK	AAC(3)-IIIa in complex with CoA and sisomicin 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside N(3)-acetyltransferase III, COENZYME A, ... 著者 Zielinski, M, Berghuis, A.M. 登録日 2021-05-05 公開日 2022-07-06 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17, 2022
7MQL	AAC(3)-IIIa in complex with CoA and neomycin 分子名称: Aminoglycoside N(3)-acetyltransferase III, COENZYME A, FORMIC ACID, ... 著者 Zielinski, M, Berghuis, A.M. 登録日 2021-05-05 公開日 2022-07-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17, 2022
7MXO	CryoEM structure of human NKCC1 分子名称: CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 著者 Moseng, M.A. 登録日 2021-05-19 公開日 2022-09-28 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022

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