3SO6
Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain
Summary for 3SO6
Entry DOI | 10.2210/pdb3so6/pdb |
Descriptor | LDL receptor adaptor protein, Low-density lipoprotein receptor (3 entities in total) |
Functional Keywords | ptb, endocytic adaptor, receptor, ldl, ldlr, autosomal recessive hypercholesterolemia, arh, cholesterol, protein binding-protein transport complex, protein binding/protein transport |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cytoplasm : D3ZAR1 Cell membrane ; Single-pass type I membrane protein : P01130 |
Total number of polymer chains | 2 |
Total formula weight | 16907.69 |
Authors | Dvir, H.,Zajonc, D.M. (deposition date: 2011-06-29, release date: 2012-04-18, Last modification date: 2024-02-28) |
Primary citation | Dvir, H.,Shah, M.,Girardi, E.,Guo, L.,Farquhar, M.G.,Zajonc, D.M. Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail. Proc.Natl.Acad.Sci.USA, 109:6916-6921, 2012 Cited by PubMed: 22509010DOI: 10.1073/pnas.1114128109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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