5M24
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![BU of 5m24 by Molmil](/molmil-images/mine/5m24) | RARg mutant-S371E | 分子名称: | (9cis)-retinoic acid, CHLORIDE ION, DODECYL-ALPHA-D-MALTOSIDE, ... | 著者 | Rochel, N, Sirigu, S. | 登録日 | 2016-10-11 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptor gamma. PLoS ONE, 12, 2017
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5LG0
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![BU of 5lg0 by Molmil](/molmil-images/mine/5lg0) | Solution NMR structure of Tryptophan to Alanine mutant of Arkadia RING domain. | 分子名称: | E3 ubiquitin-protein ligase Arkadia, ZINC ION | 著者 | Birkou, M, Chasapis, C.T, Loutsidou, A.K, Bentrop, D, Lelli, M, Herrmann, T, Episkopou, V, Spyroulias, G.A. | 登録日 | 2016-07-05 | 公開日 | 2017-06-28 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity. J. Mol. Biol., 429, 2017
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7DCT
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7DCJ
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7DCI
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![BU of 7dci by Molmil](/molmil-images/mine/7dci) | |
7DCU
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![BU of 7dcu by Molmil](/molmil-images/mine/7dcu) | |
7DCS
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![BU of 7dcs by Molmil](/molmil-images/mine/7dcs) | |
2RDA
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![BU of 2rda by Molmil](/molmil-images/mine/2rda) | |
4LY1
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![BU of 4ly1 by Molmil](/molmil-images/mine/4ly1) | |
2RR9
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![BU of 2rr9 by Molmil](/molmil-images/mine/2rr9) | The solution structure of the K63-Ub2:tUIMs complex | 分子名称: | Putative uncharacterized protein UIMC1, ubiquitin | 著者 | Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M. | 登録日 | 2010-06-16 | 公開日 | 2011-07-06 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the K63-Ub2:tUIMs complex To be Published
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2RIQ
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![BU of 2riq by Molmil](/molmil-images/mine/2riq) | Crystal Structure of the Third Zinc-binding domain of human PARP-1 | 分子名称: | ETHANOL, GLYCEROL, Poly [ADP-ribose] polymerase 1, ... | 著者 | Pascal, J.M, Langelier, M.F, Servent, K.M. | 登録日 | 2007-10-12 | 公開日 | 2008-01-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A Third Zinc-binding Domain of Human Poly(ADP-ribose) Polymerase-1 Coordinates DNA-dependent Enzyme Activation. J.Biol.Chem., 283, 2008
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6XAU
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7DHS
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![BU of 7dhs by Molmil](/molmil-images/mine/7dhs) | Crystal Structure Analysis of the BRD4 | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | 登録日 | 2020-11-17 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer. Acta Pharmacol.Sin., 42, 2021
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7DBG
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![BU of 7dbg by Molmil](/molmil-images/mine/7dbg) | Yeast CRM1e (apo) in complex with Ran-RanBP1 | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, CRM1 isoform 1, ... | 著者 | Sun, Q, Lei, Y. | 登録日 | 2020-10-20 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Novel Mechanistic Observations and NES-Binding Groove Features Revealed by the CRM1 Inhibitors Plumbagin and Oridonin. J.Nat.Prod., 84, 2021
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6XML
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![BU of 6xml by Molmil](/molmil-images/mine/6xml) | Human aldolase A I98C | 分子名称: | Fructose-bisphosphate aldolase A, GLYCEROL, PHOSPHATE ION | 著者 | Meneely, K.M, Brewer, K, Lamb, A.L. | 登録日 | 2020-06-30 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population. Protein Sci., 31, 2022
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2RMA
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6XMO
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![BU of 6xmo by Molmil](/molmil-images/mine/6xmo) | Human aldolase A I98F | 分子名称: | Fructose-bisphosphate aldolase A, GLYCEROL, PHOSPHATE ION | 著者 | Meneely, K.M, Lamb, A.L. | 登録日 | 2020-06-30 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population. Protein Sci., 31, 2022
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2RMS
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![BU of 2rms by Molmil](/molmil-images/mine/2rms) | Solution structure of the mSin3A PAH1-SAP25 SID complex | 分子名称: | MSin3A-binding protein, Paired amphipathic helix protein Sin3a | 著者 | Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. | 登録日 | 2007-11-14 | 公開日 | 2008-01-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor J.Mol.Biol., 375, 2007
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7D3Y
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![BU of 7d3y by Molmil](/molmil-images/mine/7d3y) | Crystal structure of the osPHR2-osSPX2 complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | 著者 | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | 登録日 | 2020-09-21 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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6XMH
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![BU of 6xmh by Molmil](/molmil-images/mine/6xmh) | Human aldolase A wild type | 分子名称: | Fructose-bisphosphate aldolase A, GLYCEROL, PHOSPHATE ION | 著者 | Meneely, K.M, Lamb, A.L. | 登録日 | 2020-06-30 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population. Protein Sci., 31, 2022
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6XMM
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![BU of 6xmm by Molmil](/molmil-images/mine/6xmm) | Human aldolase A I98S | 分子名称: | Fructose-bisphosphate aldolase A, GLYCEROL, PHOSPHATE ION | 著者 | Meneely, K.M, Brewer, K, Lamb, A.L. | 登録日 | 2020-06-30 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population. Protein Sci., 31, 2022
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4LRG
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![BU of 4lrg by Molmil](/molmil-images/mine/4lrg) | Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide | 分子名称: | 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide, Bromodomain-containing protein 4 | 著者 | Ravichandran, S, Jayaram, H, Poy, F, Gehling, V, Hewitt, M, Vaswani, R, Leblanc, Y, Cote, A, Nasveschuk, C, Taylor, A, Harmange, J.-C, Audia, J, Pardo, E, Joshi, S, Sandy, P, Mertz, J, Sims, R, Bergeron, L, Bryant, B, Yellapuntala, S, Nandana, B.S, Birudukota, S, Albrecht, B, Bellon, S. | 登録日 | 2013-07-19 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. ACS Med Chem Lett, 4, 2013
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2RPC
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4MD8
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2RNY
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![BU of 2rny by Molmil](/molmil-images/mine/2rny) | Complex Structures of CBP Bromodomain with H4 ack20 Peptide | 分子名称: | CREB-binding protein, Histone H4 | 著者 | Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. | 登録日 | 2008-02-03 | 公開日 | 2008-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Structure, 16, 2008
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