6KM1
 
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5C86
 | | Novel fungal alcohol oxidase with catalytic diversity among the AA5 family, apo form | | 分子名称: | Kelch domain-containing protein | | 著者 | Urresti, S, Yin, D.T, LaFond, M, Derikvand, F, Berrin, G.J, Henrissat, B, Walton, P.H, Brumer, H, Davies, G.J. | | 登録日 | 2015-06-25 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family.
Nat Commun, 6, 2015
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6K95
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4KLG
 | | DNA polymerase beta matched product complex with Mg2+, 40 s | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Freudenthal, B.D, Beard, W.A, Shock, D.D, Wilson, S.H. | | 登録日 | 2013-05-07 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Observing a DNA polymerase choose right from wrong.
Cell(Cambridge,Mass.), 154, 2013
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3V3E
 | | Crystal Structure of the Human Nur77 Ligand-binding Domain | | 分子名称: | GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | | 著者 | Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T. | | 登録日 | 2011-12-13 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
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2H6Z
 | | Crystal Structure of Thioredoxin Mutant E44D in Hexagonal (p61) Space Group | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin | | 著者 | Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | | 登録日 | 2006-06-01 | | 公開日 | 2007-05-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.
Biophys.J., 89, 2005
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2H7C
 | | Crystal structure of human carboxylesterase in complex with Coenzyme A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, ... | | 著者 | Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R. | | 登録日 | 2006-06-02 | | 公開日 | 2006-08-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
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6WDO
 | | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | | 分子名称: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | | 著者 | Feng, L, Zhang, J, Fan, M. | | 登録日 | 2020-04-01 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
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3QPM
 | | Crystal structure of peroxiredoxin Prx4 from Pseudosciaena crocea | | 分子名称: | GLYCEROL, Peroxiredoxin | | 著者 | Lian, F.M, Teng, Y.B, Jiang, Y.L, He, Y.X, Chen, Y, Zhou, C.Z. | | 登録日 | 2011-02-14 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The N-terminal beta-sheet of peroxiredoxin Prx4 in the large yellow croaker Pseudosciaena crocea is critical for its peroxidase and anti-bacterial activities
To be Published
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1GID
 | | CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING | | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN | | 著者 | Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A. | | 登録日 | 1996-08-22 | | 公開日 | 1996-12-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
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4K34
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3US9
 | | Crystal Structure of the NCX1 Intracellular Tandem Calcium Binding Domains(CBD12) | | 分子名称: | CALCIUM ION, Sodium/calcium exchanger 1 | | 著者 | Giladi, M, Sasson, Y, Hirsch, J.A, Khananshvili, D. | | 登録日 | 2011-11-23 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | A common Ca2+-driven interdomain module governs eukaryotic NCX regulation.
Plos One, 7, 2012
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5C44
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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6WI9
 | | Human secretin receptor Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Belousoff, M.J, Khoshouei, M. | | 登録日 | 2020-04-09 | | 公開日 | 2020-08-12 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure and dynamics of the active Gs-coupled human secretin receptor.
Nat Commun, 11, 2020
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3J1N
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3NE5
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6T3P
 | | Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) | | 分子名称: | Aldo-keto reductase family 1 member B1, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Hubert, L.-S, Ley, M, Heine, A, Klebe, G. | | 登録日 | 2019-10-11 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
To Be Published
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6T4O
 | | Human Carbonic anhydrase II bound by 3,5-dimethylbenzenesulfonamide | | 分子名称: | 3,5-dimethylbenzenesulfonamide, BICINE, DIMETHYL SULFOXIDE, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2019-10-14 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.133 Å) | | 主引用文献 | Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle.
Biophys.J., 119, 2020
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3UTO
 | | Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26) | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Castelmur, E, Barbieri, S, Mayans, O. | | 登録日 | 2011-11-26 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3INK
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1ZFK
 | | carbonic anhydrase II in complex with N-4-sulfonamidphenyl-N'-4-methylbenzosulfonylurease as sulfonamide inhibitor | | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase II, GLYCEROL, ... | | 著者 | Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T. | | 登録日 | 2005-04-20 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | carbonic anhydrase II in complex with N-4-sulfonamidphenyl-N'-4-methylbenzosulfonylurease as sulfonamide inhibitor
To be Published
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6JZB
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1S6A
 | | The X-ray structure of the cyanobacteria Synechocystis hemoglobin "cyanoglobin" with azide ligand | | 分子名称: | AZIDE ION, CITRATE ANION, Cyanoglobin, ... | | 著者 | Trent III, J.T, Kundu, S, Hoy, J.A, Hargrove, M.S. | | 登録日 | 2004-01-22 | | 公開日 | 2004-09-21 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystallographic analysis of synechocystis cyanoglobin reveals the structural changes accompanying ligand binding in a hexacoordinate hemoglobin.
J.Mol.Biol., 341, 2004
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1S96
 | | The 2.0 A X-ray structure of Guanylate Kinase from E.coli | | 分子名称: | Guanylate kinase, PHOSPHATE ION, UNKNOWN ATOM OR ION | | 著者 | Kreusch, A, Spraggon, G, Klock, H.E, McMullan, D, Vincent, J, Rodrigues, K, Lesley, S.A. | | 登録日 | 2004-02-03 | | 公開日 | 2004-02-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure of Guanylate Kinase from Escherichia coli at 2.0 A resolution
To be Published
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3Q65
 | | Human Aldose Reductase in Complex with NADP+ in Space Group P212121 | | 分子名称: | Aldose reductase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sawaya, M.R, Cascio, D, Balendiran, G.K. | | 登録日 | 2010-12-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The role of Cys-298 in aldose reductase function.
J.Biol.Chem., 286, 2011
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