6WI9

Human secretin receptor Gs complex

Summary for 6WI9

Entry DOI	10.2210/pdb6wi9/pdb
EMDB information	21683
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	gpcr, gs coupled, complex, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	161076.54
Authors	Belousoff, M.J.,Khoshouei, M. (deposition date: 2020-04-09, release date: 2020-08-12, Last modification date: 2020-09-02)
Primary citation	Dong, M.,Deganutti, G.,Piper, S.J.,Liang, Y.L.,Khoshouei, M.,Belousoff, M.J.,Harikumar, K.G.,Reynolds, C.A.,Glukhova, A.,Furness, S.G.B.,Christopoulos, A.,Danev, R.,Wootten, D.,Sexton, P.M.,Miller, L.J. Structure and dynamics of the active Gs-coupled human secretin receptor. Nat Commun, 11:4137-4137, 2020 Cited by PubMed: 32811827 DOI: 10.1038/s41467-020-17791-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.3 Å)

Structure validation