3V3E

Crystal Structure of the Human Nur77 Ligand-binding Domain

Summary for 3V3E

• Entry DOI: 10.2210/pdb3v3e/pdb
• Related: 3V3Q
• Descriptor: Nuclear receptor subfamily 4 group A member 1, GLYCEROL (3 entities in total)
• Functional Keywords: orphan nuclear receptor, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P22736
• Total number of polymer chains: 2
• Total formula weight: 57766.89

Authors

Zhang, Q.,Shi, C.,Yang, K.,Chen, Y.,Zhan, Y.,Wu, Q.,Lin, T. (deposition date: 2011-12-13, release date: 2012-09-26, Last modification date: 2023-11-08)

• Primary citation: Zhan, Y.,Chen, Y.,Zhang, Q.,Zhuang, J.,Tian, M.,Chen, H.,Zhang, L.,Zhang, H.,He, J.,Wang, W.,Wu, R.,Wang, Y.,Shi, C.,Yang, K.,Li, A.,Xin, Y.,Li, T.Y.,Yang, J.Y.,Zheng, Z.,Yu, C.,Lin, S.,Chang, C.,Huang, P.,Lin, T.,Wu, Q.; The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK; Nat.Chem.Biol., 8:897-904, 2012; PubMed: 22983157; DOI: 10.1038/nchembio.1069

Experimental method

X-RAY DIFFRACTION (2.06 Å)