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5T89
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Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ...
著者Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K.
登録日2016-09-07
公開日2017-02-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.
Structure, 25, 2017
8BXR
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Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region
分子名称: 1,2-ETHANEDIOL, Titin
著者Mayans, O, Fleming, J.R, Williams, R.
登録日2022-12-09
公開日2023-02-15
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
7RAM
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Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
分子名称: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
著者Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
登録日2021-07-02
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
7LBF
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CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ...
著者Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C.
登録日2021-01-07
公開日2021-03-10
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.
Cell, 184, 2021
4EDQ
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MBP-fusion protein of myosin-binding protein c residues 149-269
分子名称: Maltose-binding periplasmic protein,Myosin-binding protein C, cardiac-type chimeric protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2012-03-27
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献MBP-fusion protein of myosin-binding protein c residues 149-269
To be Published
3ZYI
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NetrinG2 in complex with NGL2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4, ...
著者Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
登録日2011-08-23
公開日2011-10-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions
Embo J., 30, 2011
3ZYJ
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NetrinG1 in complex with NGL1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C, ...
著者Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
登録日2011-08-23
公開日2011-10-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
5W59
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Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c
分子名称: Fibroblast growth factor 9, Fibroblast growth factor receptor 1, SULFATE ION
著者Mohammadi, M, Ma, J, Liu, Y.
登録日2017-06-14
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization.
Structure, 25, 2017
7ZA2
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GPC3-Unc5D octamer structure and role in cell migration
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
著者Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
登録日2022-03-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7YSU
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Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ...
著者Mohammadi, M, Chen, L.
登録日2022-08-13
公開日2023-04-19
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for FGF hormone signalling.
Nature, 618, 2023
7YSH
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Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, COPPER (II) ION, Fibroblast growth factor 23, ...
著者Mohammadi, M, Chen, L.
登録日2022-08-12
公開日2023-04-19
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural basis for FGF hormone signalling.
Nature, 618, 2023
7YSW
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Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ...
著者Mohammadi, M, Chen, L.
登録日2022-08-13
公開日2023-06-14
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural basis for FGF hormone signalling.
Nature, 618, 2023
7TIT
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Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C
分子名称: Myosin-binding protein C, cardiac-type, cardiac actin, ...
著者Risi, C.M, Galkin, V.E.
登録日2022-01-14
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TJ7
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Cardiac thin filament decorated with C1 Ig-domain and regulatory M-domain of cardiac myosin binding protein C (cMyBP-C)
分子名称: Myosin-binding protein C, cardiac-type, cardiac actin, ...
著者Risi, C.M, Galkin, V.E.
登録日2022-01-14
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TIJ
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Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C
分子名称: Myosin-binding protein C, cardiac-type, cardiac actin
著者Risi, C.M, Galkin, V.E.
登録日2022-01-13
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
5FM5
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BU of 5fm5 by Molmil
Crystal structure of the myomesin:obscurin-like-1 complex
分子名称: MYOMESIN-1, OBSCURIN-LIKE-1
著者Pernigo, S, Steiner, R.A.
登録日2015-11-01
公開日2016-11-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Structure, 25, 2017
6IAA
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hRobo2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Barak, R, Isupov, N.M, Opatowsky, Y.
登録日2018-11-26
公開日2019-03-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
6U7N
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Crystal structure of neurotrimin (NTM)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ...
著者Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S.
登録日2019-09-03
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020
5FTT
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Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ...
著者Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E.
登録日2016-01-15
公開日2016-05-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
7ZA1
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GPC3-Unc5D octamer structure and role in cell migration
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
著者Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
登録日2022-03-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7ZA3
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GPC3-Unc5D octamer structure and role in cell migration
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
著者Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
登録日2022-03-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
1KOA
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TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS
分子名称: TWITCHIN
著者Kobe, B, Heierhorst, J, Feil, S.C, Parker, M.W, Benian, G.M, Weiss, K.R, Kemp, B.E.
登録日1996-06-28
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
6CXI
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Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 1
分子名称: Actin, cytoplasmic 2, Myosin-binding protein C, ...
著者Galkin, V.E, Schroeder, G.F.
登録日2018-04-03
公開日2018-10-10
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.
Structure, 26, 2018
6CXJ
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Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 2
分子名称: Actin, cytoplasmic 2, Myosin-binding protein C, ...
著者Galkin, V.E, Schroeder, G.F.
登録日2018-04-03
公開日2018-10-10
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.
Structure, 26, 2018
1NUN
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Crystal Structure Analysis of the FGF10-FGFR2b Complex
分子名称: Fibroblast growth factor-10, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ...
著者Yeh, B.K, Igarashi, M, Eliseenkova, A.V, Plotnikov, A.N, Sher, I, Ron, D, Aaronson, S.A, Mohammadi, M.
登録日2003-01-31
公開日2003-02-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.
Proc.Natl.Acad.Sci.USA, 100, 2003

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