PDB: 392 件ウェブページステータス検索Chemie searchBIRD

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8A78	PcIDS1_F315A in complex with Mg2+/Mn2+ and GPP 分子名称: GERANYL DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A74	PcIDS1_F315A in complex with Mg2+ and GPP 分子名称: GERANYL DIPHOSPHATE, Isoprenyl diphosphate synthase, MAGNESIUM ION 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7B	PcIDS1_D319N in complex with Mg2+ and 3-Br-GPP 分子名称: CARBONATE ION, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7J	PcIDS1 in complex with Mn2+, IPP, and ZOL 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
1UBY	STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE 分子名称: DIMETHYLALLYL DIPHOSPHATE, FARNESYL DIPHOSPHATE SYNTHASE, MAGNESIUM ION 著者 Tarshis, L.C, Proteau, P, Poulter, C.D, Sacchettini, J.C. 登録日 1996-10-14 公開日 1997-03-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Regulation of product chain length by isoprenyl diphosphate synthases. Proc.Natl.Acad.Sci.USA, 93, 1996
1UBV	STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE 分子名称: FARNESYL DIPHOSPHATE SYNTHASE 著者 Tarshis, L.C, Proteau, P, Poulter, C.D, Sacchettini, J.C. 登録日 1996-10-14 公開日 1997-03-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of product chain length by isoprenyl diphosphate synthases. Proc.Natl.Acad.Sci.USA, 93, 1996
1RTR	Crystal Structure of S. Aureus Farnesyl Pyrophosphate Synthase 分子名称: geranyltranstransferase 著者 Hosfield, D.J, Zhang, Y, Dougan, D.R, Brooun, A, Tari, L.W, Swanson, R.V, Finn, J. 登録日 2003-12-10 公開日 2004-03-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis J.Mol.Biol., 279, 2004
1RQJ	Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Risedronate 分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranyltranstransferase, ... 著者 Hosfield, D.J, Zhang, Y, Dougan, D.R, Brooun, A, Tari, L.W, Swanson, R.V, Finn, J. 登録日 2003-12-05 公開日 2004-03-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis J.Biol.Chem., 279, 2004
1UBX	STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE 分子名称: FARNESYL DIPHOSPHATE, FARNESYL DIPHOSPHATE SYNTHASE, MAGNESIUM ION 著者 Tarshis, L.C, Proteau, P, Poulter, C.D, Sacchettini, J.C. 登録日 1996-10-14 公開日 1997-03-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of product chain length by isoprenyl diphosphate synthases. Proc.Natl.Acad.Sci.USA, 93, 1996
1UBW	STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE 分子名称: FARNESYL DIPHOSPHATE SYNTHASE, GERANYL DIPHOSPHATE, MAGNESIUM ION 著者 Tarshis, L.C, Proteau, P, Poulter, C.D, Sacchettini, J.C. 登録日 1996-10-14 公開日 1997-03-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of product chain length by isoprenyl diphosphate synthases. Proc.Natl.Acad.Sci.USA, 93, 1996
1V4E	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-13 公開日 2004-03-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1V4I	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima F132A mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1V4K	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima S77F mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1V4J	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima V73Y mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1VG6	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A mutant 分子名称: octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
1VG2	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y mutant 分子名称: octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
1V4H	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima F52A mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1VG4	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A mutant 分子名称: octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
1VG7	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A/D62A mutant 分子名称: octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
1VG3	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y/S77F mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
2Z4W	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, [(6E,11E)-2,6,12,16-tetramethylheptadeca-2,6,11,15-tetraene-9,9-diyl]bis(phosphonic acid) 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z7I	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-742 分子名称: (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Guo, R.T, Chen, C.K.-M, Ko, T.-P, Cao, R, Hudock, M, Oldfield, E, Wang, A.H.-J. 登録日 2007-08-23 公開日 2008-07-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z7H	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-210 分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, {1-HYDROXY-3-[METHYL(4-PHENYLBUTYL)AMINO]PROPANE-1,1-DIYL}BIS(PHOSPHONIC ACID) 著者 Cao, R, Chen, C.K.-M, Guo, R.-T, Hudock, M, Wang, A.H.-J, Oldfield, E. 登録日 2007-08-23 公開日 2008-05-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins, 73, 2008
2ZEU	S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with BPH-715 分子名称: 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Geranylgeranyl pyrophosphate synthetase 著者 Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-12-17 公開日 2008-12-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation J.Am.Chem.Soc., 131, 2009
2Z50	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-28 分子名称: (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase 著者 Guo, R.T, Chen, C.K.-M, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008

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