PDB: 2718 件ウェブページステータス検索Chemie searchBIRD

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3QKI	Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7 分子名称: Glucose-6-phosphate isomerase 著者 Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC) 登録日 2011-02-01 公開日 2011-02-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7 TO BE PUBLISHED
1L5R	Human liver glycogen phosphorylase a complexed with riboflavin, N-Acetyl-beta-D-Glucopyranosylamine and CP-403,700 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, N-acetyl-beta-D-glucopyranosylamine, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Ekstrom, J.L, Pauly, T.A, Carty, M.D, Soeller, W.C, Culp, J, Danley, D.E, Hoover, D.J, Treadway, J.L, Gibbs, E.M, Fletterick, R.J, Day, Y.S.N, Myszka, D.G, Rath, V.L. 登録日 2002-03-07 公開日 2002-12-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase. Chem.Biol., 9, 2002
1ZZG	Crystal structure of hypothetical protein TT0462 from Thermus thermophilus HB8 分子名称: glucose-6-phosphate isomerase 著者 Yamamoto, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-06-14 公開日 2006-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of hypothetical protein TT0462 from Thermus thermophilus HB8 To be Published
1L5V	Crystal Structure of the Maltodextrin Phosphorylase complexed with Glucose-1-phosphate 分子名称: 1-O-phosphono-alpha-D-glucopyranose, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MALTODEXTRIN PHOSPHORYLASE, ... 著者 Geremia, S, Campagnolo, M, Schinzel, R, Johnson, L.N. 登録日 2002-03-08 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase J.Mol.Biol., 322, 2002
1L7X	Human liver glycogen phosphorylase b complexed with caffeine, N-acetyl-beta-D-glucopyranosylamine, and CP-403,700 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CAFFEINE, Glycogen phosphorylase, ... 著者 Ekstrom, J.L, Pauly, T.A, Carty, M.D, Soeller, W.C, Culp, J, Danley, D.E, Hoover, D.J, Treadway, J.L, Gibbs, E.M, Fletterick, R.J, Day, Y.S.N, Myszka, D.G, Rath, V.L. 登録日 2002-03-18 公開日 2002-12-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase. Chem.Biol., 9, 2002
1KOJ	Crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonohydroxamic acid 分子名称: 5-PHOSPHO-D-ARABINOHYDROXAMIC ACID, Glucose-6-phosphate isomerase 著者 Arsenieva, D, Hardre, R, Salmon, L, Jeffery, C.J. 登録日 2001-12-20 公開日 2002-05-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonohydroxamic acid. Proc.Natl.Acad.Sci.USA, 99, 2002
2Z78	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-806 分子名称: 3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2,2-diphosphonoethyl)pyridinium, Geranylgeranyl pyrophosphate synthetase 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-08-16 公開日 2008-07-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z4V	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GGPP (inhibitory site) 分子名称: GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z52	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-23 分子名称: (1-HYDROXYDODECANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Guo, R.T, Chen, C.K.-M, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
1ZW5	X-ray structure of Farnesyl diphosphate synthase protein 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, ZOLEDRONIC ACID, ... 著者 Kavanagh, K.L, Guo, K, Wu, X, von Delft, F, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2005-06-03 公開日 2005-06-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc.Natl.Acad.Sci.USA, 103, 2006
2Z4X	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 (P21) 分子名称: (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Guo, R.T, Chen, C.K.-M, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
1L5W	Crystal Structure of the Maltodextrin Phosphorylase Complexed with the Products of the Enzymatic Reaction between Glucose-1-phosphate and Maltotetraose 分子名称: MALTODEXTRIN PHOSPHORYLASE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Geremia, S, Campagnolo, M, Schinzel, R, Johnson, L.N. 登録日 2002-03-08 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase J.Mol.Biol., 322, 2002
7GPB	STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP 分子名称: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Barford, D, Hu, S.-H, Johnson, L.N. 登録日 1990-11-13 公開日 1992-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991
2XV7	Crystal structure of vascular endothelial growth factor D 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR D, alpha-D-mannopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Leppanen, V.-M, Jeltsch, M, Anisimov, A, Tvorogov, D, Aho, K, Kalkkinen, N, Toivanen, P, Yla-Herttuala, S, Ballmer-Hofer, K, Alitalo, K. 登録日 2010-10-23 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Determinants of Vascular Endothelial Growth Factor-D - Receptor Binding and Specificity. Blood, 117, 2011
1L6I	Crystal Structure of the Maltodextrin Phosphorylase complexed with the products of the enzymatic reaction between glucose-1-phosphate and maltopentaose 分子名称: MALTODEXTRIN PHOSPHORYLASE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Geremia, S, Campagnolo, M, Schinzel, R, Johnson, L.N. 登録日 2002-03-11 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase J.Mol.Biol., 322, 2002
5DGN	Crystal structure of human FPPS in complex with compound 13 分子名称: 8-(naphthalen-1-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-08-28 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
3PDE	Crystal structure of geranylgeranyl pyrophosphate synthase from Lactobacillus brevis atcc 367 complexed with isoprenyl diphosphate and magnesium 分子名称: DIMETHYLALLYL DIPHOSPHATE, Farnesyl-diphosphate synthase, GLYCEROL, ... 著者 Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-10-22 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
21BI	INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY ALA) (C71A) 分子名称: INTERLEUKIN-1 BETA 著者 Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y. 登録日 1991-03-21 公開日 1992-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献
3NPA	Glycogen phosphorylase complexed with 2,5-dihydroxy-4-(beta-D-glucopyranosyl)-bromo-benzene 分子名称: (1S)-1,5-anhydro-1-(4-bromo-2,5-dihydroxyphenyl)-D-glucitol, Glycogen phosphorylase, muscle form 著者 Alexacou, K.-M. 登録日 2010-06-28 公開日 2011-06-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.969 Å) 主引用文献 Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase. Bioorg.Med.Chem., 19, 2011
2Z7I	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-742 分子名称: (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Guo, R.T, Chen, C.K.-M, Ko, T.-P, Cao, R, Hudock, M, Oldfield, E, Wang, A.H.-J. 登録日 2007-08-23 公開日 2008-07-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z4W	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, [(6E,11E)-2,6,12,16-tetramethylheptadeca-2,6,11,15-tetraene-9,9-diyl]bis(phosphonic acid) 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
3OAC	Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... 著者 Hsieh, F.-L, Chang, T.-H, Ko, T.-P, Wang, A.H.-J. 登録日 2010-08-05 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions J.Mol.Biol., 404, 2010
5DGM	Crystal structure of human FPPS in complex with monophosphonate compound 7 分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, {2-[(phosphonomethyl)carbamoyl]-1H-benzo[g]indol-1-yl}acetic acid 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-08-28 公開日 2016-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 A General Strategy for Targeting Drugs to Bone. Angew.Chem.Int.Ed.Engl., 54, 2015
5DIQ	Crystal structure of human FPPS in complex with salicylic acid derivative 3a 分子名称: 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-01 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
5DJP	Crystal structure of human FPPS in complex with biaryl compound 5 分子名称: 4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015

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