PDB: 533 件ウェブページステータス検索Chemie searchBIRD

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3VS5	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, Tyrosine-protein kinase HCK 著者 Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS2	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Niwa, H, Parker, J.L, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VRZ	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea 分子名称: 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.218 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VRY	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane 分子名称: 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Niwa, H, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.481 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
4EIK	Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12 分子名称: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide 著者 Camara-Artigas, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex. Acta Crystallogr F Struct Biol Commun, 72, 2016
2LQW	Solution structure of phosphorylated CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-16 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LQN	Solution structure of CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-09 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LP5	Native Structure of the Fyn SH3 A39V/N53P/V55L 分子名称: Tyrosine-protein kinase Fyn 著者 Neudecker, P, Robustelli, P, Cavalli, A, Vendruscolo, M, Kay, L.E. 登録日 2012-02-06 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of an intermediate state in protein folding and aggregation. Science, 336, 2012
4D8D	Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant 分子名称: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn 著者 Arold, S.T, Hoh, F, Dumas, C. 登録日 2012-01-10 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5201 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
4D8K	Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution 分子名称: GLYCEROL, SULFATE ION, Tyrosine-protein kinase Lck 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-01-10 公開日 2012-01-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution To be published
2LMJ	Itk-sh3 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Kristiansen, P, Bie Andersen, T, Huszenicza, Z, Andreotti, A.H, Spurkland, A. 登録日 2011-12-05 公開日 2012-12-05 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The SH3 domains of the Tec family kinase Itk and the Src family kinase Lck compete for adjacent sites on T-cell specific adapter protein To be Published
4A63	Crystal structure of the p73-ASPP2 complex at 2.6A resolution 分子名称: ACETATE ION, APOPTOSIS STIMULATING OF P53 PROTEIN 2, TUMOUR PROTEIN 73, ... 著者 Canning, P, Sharpe, T, Krojer, T, Savitsky, P, Cooper, C.D.O, Salah, E, Keates, T, Muniz, J, Vollmar, M, von Delft, F, Weigelt, J, Arrowsmith, C, Bountra, C, Edwards, A, Bullock, A.N. 登録日 2011-10-31 公開日 2011-12-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73. J.Mol.Biol., 423, 2012
3UF4	Crystal structure of a SH3 and SH2 domains of FYN protein (Proto-concogene Tyrosine-protein kinase Fyn) from Mus musculus at 1.98 A resolution 分子名称: CHLORIDE ION, GLYCEROL, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-10-31 公開日 2011-12-07 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structure of a SH3 and SH2 domains of FYN protein (Proto-concogene Tyrosine-protein kinase Fyn) from Mus musculus at 1.98 A resolution To be published
3UAT	Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules 分子名称: Disks large homolog 1, phosphor-LGN peptide 著者 Shang, Y, Zhu, J, Wen, W, Zhang, M. 登録日 2011-10-22 公開日 2011-12-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules Embo J., 2011
3UA7	Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein 分子名称: CHLORIDE ION, FORMIC ACID, GLYCEROL, ... 著者 Martin-Garcia, J.M, Ruiz-Sanz, J, Luque, I, Camara-Artigas, A. 登録日 2011-10-21 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein. Acta Crystallogr.,Sect.D, 68, 2012
3UA6	Crystal Structure of the Human Fyn SH3 domain 分子名称: FORMIC ACID, GLYCEROL, SODIUM ION, ... 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2011-10-21 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein. Acta Crystallogr.,Sect.D, 68, 2012
3TVT	Structural basis for Discs Large interaction with Pins 分子名称: Disks large 1 tumor suppressor protein, Partner of Inscuteable 著者 Johnston, C.A, Doe, C.Q, Prehoda, K.E. 登録日 2011-09-20 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for Discs Large interaction with Pins To be Published
2LJ3	PFBD: High-throughput Strategy of Backbone fold Determination for small well-folded proteins in less than a day 分子名称: Spectrin alpha chain, brain 著者 Kumar, D, Hosur, R. 登録日 2011-09-04 公開日 2011-12-07 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 PFBD: High-throughput Strategy of Backbone fold Determination for small well-folded proteins in less than a day To be Published
3THK	Structure of SH3 chimera with a type II ligand linked to the chain C-terminal 分子名称: BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ... 著者 Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V. 登録日 2011-08-19 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide. J.Biomol.Struct.Dyn., 29, 2011
2LCS	Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p 分子名称: NAP1-binding protein 2, Serine/threonine-protein kinase STE20 著者 Gorelik, M, Davidson, A.R. 登録日 2011-05-07 公開日 2012-02-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Distinct Peptide Binding Specificities of Src Homology 3 (SH3) Protein Domains Can Be Determined by Modulation of Local Energetics across the Binding Interface. J.Biol.Chem., 287, 2012
3REB	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
3REA	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
3RBB	HIV-1 NEF protein in complex with engineered HCK SH3 domain 分子名称: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK 著者 Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. 登録日 2011-03-29 公開日 2011-04-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly. Traffic, 12, 2011
3QWX	CED-2 1-174 分子名称: Cell death abnormality protein 2, SULFATE ION 著者 Kang, Y, Sun, J, Liu, Y. 登録日 2011-02-28 公開日 2011-06-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans. Biochem.Biophys.Res.Commun., 410, 2011
3QWY	CED-2 分子名称: Cell death abnormality protein 2, GLYCEROL, SULFATE ION 著者 Kang, Y, Sun, J, Liu, Y, Sun, D, Hu, Y, Liu, Y.F. 登録日 2011-02-28 公開日 2011-06-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans. Biochem.Biophys.Res.Commun., 410, 2011

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