PDB: 1500 件ウェブページステータス検索Chemie searchBIRD

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5XJQ	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2/F/E/G from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Yi, H, Zhang, R. 登録日 2017-05-04 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
8ID2	Crystal structure of the ubiquitin-like domain in the SF3A1 subunit of human U2 snRNP complexed with the stem-loop 4 of U1 snRNA 分子名称: RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3'), Splicing factor 3A subunit 1 著者 Terawaki, S, Nameki, N, Kuwasako, K. 登録日 2023-02-12 公開日 2023-05-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP. J.Biochem., 174, 2023
4F7U	The 6S snRNP assembly intermediate 分子名称: HEXAETHYLENE GLYCOL, Methylosome subunit pICln, Small nuclear ribonucleoprotein E, ... 著者 Grimm, C, Pelz, J.P. 登録日 2012-05-16 公開日 2013-01-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Structural Basis of Assembly Chaperone- Mediated snRNP Formation. Mol.Cell, 49, 2013
5XJS	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Yi, H, Zhang, R. 登録日 2017-05-04 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
7B0Y	Structure of a transcribing RNA polymerase II-U1 snRNP complex 分子名称: 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... 著者 Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. 登録日 2020-11-23 公開日 2021-01-13 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
8Q7V	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7Q	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-16 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7X	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7W	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
6PPN	Structure of S. pombe Lsm2-8 with unprocessed U6 snRNA 分子名称: Mimic of unprocessed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
3SWN	Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings 分子名称: U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, ... 著者 Mund, M, Neu, A, Ullmann, J.L, Neu, U, Sprangers, R. 登録日 2011-07-14 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings. J.Mol.Biol., 414, 2011
6PPQ	Structure of S. pombe Lsm1-7 with RNA, polyuridine with 3' adenosine 分子名称: Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, RNA (5'-R(*UP*UP*UP*UP*UP*A)-3'), ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
6PPV	Structure of S. pombe Lsm1-7 with RNA, polyuridine with 3' guanosine 分子名称: Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, RNA (5'-R(*AP*UP*UP*UP*UP*G)-3'), ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
6PPP	Structure of S. pombe Lsm2-8 with processed U6 snRNA 分子名称: Mimic of processed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
8G1U	Structure of the methylosome-Lsm10/11 complex 分子名称: ADENOSINE, Methylosome protein 50, Methylosome subunit pICln, ... 著者 Lin, M, Paige, A, Tong, L. 登録日 2023-02-03 公開日 2023-08-23 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome. Rna, 29, 2023
8Q91	Structure of the human 20S U5 snRNP core 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-08-19 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
8RC0	Structure of the human 20S U5 snRNP 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-12-05 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
7B0I	Structure of a minimal SF3B core in complex with spliceostatin A (form II) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3,Splicing factor 3B subunit 3,Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-11-19 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
3E66	Crystal structure of the beta-finger domain of yeast Prp8 分子名称: PRP8 著者 Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R. 登録日 2008-08-14 公開日 2008-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc.Natl.Acad.Sci.Usa, 105, 2008
3SBT	Crystal structure of a Aar2-Prp8 complex 分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, S-1,2-PROPANEDIOL, ... 著者 Weber, G, Santos, K.F, Holton, N, Wahl, M.C. 登録日 2011-06-06 公開日 2011-07-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev., 25, 2011
6TEO	Crystal structure of a yeast Snu114-Prp8 complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... 著者 Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. 登録日 2019-11-12 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
1N9R	Crystal structure of a heptameric ring complex of yeast SmF in spacegroup P4122 分子名称: Small nuclear ribonucleoprotein F 著者 Collins, B.M, Cubeddu, L, Naidoo, N, Harrop, S.J, Kornfeld, G.D, Dawes, I.W, Curmi, P.M.G, Mabbutt, B.C. 登録日 2002-11-26 公開日 2002-12-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: Crystal structure of an oligomeric complex of yeast SmF J.Biol.Chem., 278, 2003
1N9S	Crystal structure of yeast SmF in spacegroup P43212 分子名称: Small nuclear ribonucleoprotein F 著者 Collins, B.M, Cubeddu, L, Naidoo, N, Harrop, S.J, Kornfeld, G.D, Dawes, I.W, Curmi, P.M.G, Mabbutt, B.C. 登録日 2002-11-26 公開日 2002-12-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: Crystal structure of an oligomeric complex of yeast SmF J.Biol.Chem., 278, 2003
2X7K	The crystal structure of PPIL1 in complex with cyclosporine A suggests a binding mode for SKIP 分子名称: CADMIUM ION, CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1, ... 著者 Stegmann, C.M, Luehrmann, R, Wahl, M.C. 登録日 2010-03-01 公開日 2010-03-23 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 The Crystal Structure of Ppil1 Bound to Cyclosporine a Suggests a Binding Mode for a Linear Epitope of the Skip Protein. Plos One, 5, 2010
7B9C	Structure of a minimal SF3B core in complex with spliceostatin A (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-14 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021

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