8ID2

Crystal structure of the ubiquitin-like domain in the SF3A1 subunit of human U2 snRNP complexed with the stem-loop 4 of U1 snRNA

Summary for 8ID2

• Entry DOI: 10.2210/pdb8id2/pdb
• Descriptor: Splicing factor 3A subunit 1, RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3') (3 entities in total)
• Functional Keywords: splicing, uncg tetraloop, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 41381.08

Authors

Terawaki, S.,Nameki, N.,Kuwasako, K. (deposition date: 2023-02-12, release date: 2023-05-17, Last modification date: 2023-08-09)

• Primary citation: Nameki, N.,Terawaki, S.I.,Takizawa, M.,Kitamura, M.,Muto, Y.,Kuwasako, K.; Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP.; J.Biochem., 174:203-216, 2023; PubMed: 37094335; DOI: 10.1093/jb/mvad033

Experimental method

X-RAY DIFFRACTION (1.8 Å)