8ID2

Crystal structure of the ubiquitin-like domain in the SF3A1 subunit of human U2 snRNP complexed with the stem-loop 4 of U1 snRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Splicing factor 3A subunit 1	polymer	117	13061.0	2	UniProt (Q15459) Pfam (PF00240)	Homo sapiens (human)	SF3a120,Spliceosome-associated protein 114,SAP 114
2	C, D (C, D)	RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3')	polymer	24	7629.5	2		Homo sapiens
3	E, F, G, H (A, B, C, D)	water	water		18.0	100	Chemie (HOH)

Sequence modifications

A, B: 703 - 793 (UniProt: Q15459)

PDB	External Database	Details
Met 677	-	initiating methionine
Gly 678	-	expression tag
Ser 679	-	expression tag
Ser 680	-	expression tag
His 681	-	expression tag
His 682	-	expression tag
His 683	-	expression tag
His 684	-	expression tag
His 685	-	expression tag
His 686	-	expression tag
Ser 687	-	expression tag
Ser 688	-	expression tag
Gly 689	-	expression tag
Leu 690	-	expression tag
Val 691	-	expression tag
Pro 692	-	expression tag
Arg 693	-	expression tag
Gly 694	-	expression tag
Ser 695	-	expression tag
His 696	-	expression tag
Glu 697	-	expression tag
Asn 698	-	expression tag
Leu 699	-	expression tag
Tyr 700	-	expression tag
Phe 701	-	expression tag
Gln 702	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	41381.1
All*	Total formula weight	41381.1

*Water molecules are not included.