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1K4B
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STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES
分子名称: 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3'
著者Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
登録日2001-10-07
公開日2001-12-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1K4A
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STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES
分子名称: 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3'
著者Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
登録日2001-10-07
公開日2001-12-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
3PIF
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BU of 3pif by Molmil
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese
分子名称: 5'->3' EXORIBONUCLEASE (xrn1), MANGANESE (II) ION
著者Chang, J.H, Xiang, S, Tong, L.
登録日2010-11-06
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
3PIE
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Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant
分子名称: 5'->3' EXORIBONUCLEASE (Xrn1)
著者Chang, J.H, Xiang, S, Tong, L.
登録日2010-11-06
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
2NUB
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Structure of Aquifex aeolicus Argonuate
分子名称: Argonaute
著者Rashid, U.J, Paterok, D, Koglin, A, Gohlke, H, Piehler, J, Chen, J.C.-H.
登録日2006-11-09
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Aquifex aeolicus argonaute highlights conformational flexibility of the PAZ domain as a potential regulator of RNA-induced silencing complex function.
J.Biol.Chem., 282, 2007
3HRK
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Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidyl-adenylate complex)
分子名称: CHLORIDE ION, HISTIDYL-ADENOSINE MONOPHOSPHATE, Histidyl-tRNA synthetase
著者Arakaki, T.L, Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2009-06-09
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
8A7I
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Crystal structure of BRD9 bromodomain in complex with compound EA-89
分子名称: Bromodomain-containing protein 9, ~{N}-[1,1-bis(oxidanylidene)thian-4-yl]-7-[3-methyl-1-(piperidin-4-ylmethyl)indol-5-yl]-4-oxidanylidene-5-propyl-thieno[3,2-c]pyridine-2-carboxamide
著者Faller, M, Zink, F.
登録日2022-06-21
公開日2022-08-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma.
Blood Cancer J, 12, 2022
3HR3
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Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA
分子名称: 5'-D(*GP*CP*GP*(US4)P*(OMU))P*AP*CP*GP*C)-3'
著者Egli, M, Pallan, P.S.
登録日2009-06-08
公開日2009-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.
J.Am.Chem.Soc., 131, 2009
3HRI
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Histidyl-tRNA synthetase (apo) from Trypanosoma brucei
分子名称: Histidyl-tRNA synthetase
著者Arakaki, T.L, Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2009-06-09
公開日2009-12-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
7VFT
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BU of 7vft by Molmil
Crystal structure of rGGGC(CAG)5GUCC oligo
分子名称: RNA (5'-R(*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3')
著者An, Y, Chan, H.Y.E, Ngo, J.C.K.
登録日2021-09-13
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases.
Nucleic Acids Res., 50, 2022
1RC7
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Crystal structure of RNase III Mutant E110K from Aquifex Aeolicus complexed with ds-RNA at 2.15 Angstrom Resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3', Ribonuclease III
著者Blaszczyk, J, Gan, J, Ji, X.
登録日2003-11-03
公開日2004-03-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.
Structure, 12, 2004
1RC5
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CRYSTAL STRUCTURE OF MG(II)-COMPLEX OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.30 ANGSTROM RESOLUTION
分子名称: MAGNESIUM ION, Ribonuclease III
著者Blaszczyk, J, Gan, J, Ji, X.
登録日2003-11-03
公開日2004-03-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.
Structure, 12, 2004
3KLM
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17beta-HSD1 in complex with DHT
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL
著者Mazumdar, M.
登録日2009-11-08
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
Mol.Endocrinol., 24, 2010
8BJW
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BU of 8bjw by Molmil
Structure of Tupaia Paramyxovirus C protein
分子名称: DI(HYDROXYETHYL)ETHER, Protein C
著者Bourhis, J.M, Jamin, M.
登録日2022-11-08
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization.
Biomolecules, 13, 2023
1R4K
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Solution Structure of the Drosophila Argonaute 1 PAZ Domain
分子名称: Argonaute 1
著者Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M.
登録日2003-10-07
公開日2003-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
3LC0
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Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidine complex)
分子名称: HISTIDINE, Histidyl-tRNA synthetase
著者Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-01-08
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs.
J.Mol.Biol., 397, 2010
2A0P
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Crystal structure of RNA oligomer containing 4'-thioribose
分子名称: 5'-R(*CP*CP*(S4C)P*CP*GP*GP*GP*G)-3'
著者Haeberli, P, Berger, I, Pallan, P.S, Egli, M.
登録日2005-06-16
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine
Nucleic Acids Res., 33, 2005
2A11
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Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis
分子名称: CALCIUM ION, Ribonuclease III
著者Akey, D.L, Berger, J.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-06-17
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
Protein Sci., 14, 2005
5E3H
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Structural Basis for RNA Recognition and Activation of RIG-I
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
著者Jiang, F, Miller, M.T, Marcotrigiano, J.
登録日2015-10-02
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
6ANV
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Crystal structure of anti-CRISPR protein AcrF1
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Yang, H, Patel, D.J.
登録日2017-08-14
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.265 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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Crystal structure of anti-CRISPR protein AcrF10
分子名称: anti-CRISPR protein AcrF10
著者Yang, H, Patel, D.J.
登録日2017-08-14
公開日2017-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
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Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1
分子名称: Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy3, ...
著者Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B44
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Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA
分子名称: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
著者Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex
分子名称: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
著者Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2
分子名称: Anti-CRISPR protein AcrF2, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ...
著者Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017

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