7OXI
 
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7O1C
 | | Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome-RF2 complex stalled in response to L-tryptophan | | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A. | | 登録日 | 2021-03-29 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
Nat Commun, 12, 2021
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8BH4
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7N30
 | | Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-30 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
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6XZA
 | | E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification). | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | | 登録日 | 2020-02-03 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
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8HU1
 | | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | | 登録日 | 2022-12-22 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine.
Nat.Struct.Mol.Biol., 31, 2024
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7N31
 | | Elongating 70S ribosome complex in a post-translocation (POST) conformation | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-31 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
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7OE0
 | | E. coli pre-30S delta rbfA ribosomal subunit class F | | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E. | | 登録日 | 2021-04-30 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
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8EKC
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7ZTA
 | | Structure of an Escherichia coli 70S ribosome stalled by Tetracenomycin X during translation of an MAAAPQK(C) peptide | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Leroy, E.C, Perry, T.N, Renault, T.T, Innis, C.A. | | 登録日 | 2022-05-09 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs.
Nat.Chem.Biol., 19, 2023
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6TC3
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6TBV
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7N2C
 | | Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
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7AF8
 | | Bacterial 30S ribosomal subunit assembly complex state E (head domain) | | 分子名称: | 16SrRNA (head domain of the 30S ribosome, 30S ribosomal protein S10, 30S ribosomal protein S13, ... | | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Fucini, P, Connell, S. | | 登録日 | 2020-09-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
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8P16
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure I) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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8P18
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure III) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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8P17
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure II) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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4U27
 | | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | 登録日 | 2014-07-16 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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4U26
 | | Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | 登録日 | 2014-07-16 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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7OXK
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8EYT
 | | 30S_delta_ksgA+KsgA complex | | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H. | | 登録日 | 2022-10-28 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Nat.Struct.Mol.Biol., 30, 2023
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7M5D
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5J5B
 | | Structure of the WT E coli ribosome bound to tetracycline | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Cocozaki, A, Ferguson, A. | | 登録日 | 2016-04-01 | | 公開日 | 2016-07-27 | | 最終更新日 | 2018-08-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8AM9
 | | Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome | | 分子名称: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | | 登録日 | 2022-08-03 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
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8BHJ
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