7ZTA

Structure of an Escherichia coli 70S ribosome stalled by Tetracenomycin X during translation of an MAAAPQK(C) peptide

This is a non-PDB format compatible entry.

Summary for 7ZTA

• Entry DOI: 10.2210/pdb7zta/pdb
• EMDB information: 14956
• Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (64 entities in total)
• Functional Keywords: antibiotic, translation, ribosome, tetracenomycin x, protein synthesis inhibitor
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 57
• Total formula weight: 2202995.77

Authors

Leroy, E.C.,Perry, T.N.,Renault, T.T.,Innis, C.A. (deposition date: 2022-05-09, release date: 2023-04-12, Last modification date: 2024-04-24)

• Primary citation: Leroy, E.C.,Perry, T.N.,Renault, T.T.,Innis, C.A.; Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs.; Nat.Chem.Biol., 19:1091-1096, 2023; PubMed: 37322159; DOI: 10.1038/s41589-023-01343-0

Experimental method

ELECTRON MICROSCOPY (2.7 Å)