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PDB: 328 件

5EGG
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BU of 5egg by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UBCH5C
分子名称: Ubiquitin-conjugating enzyme E2 D3
著者Zhu, L, Li, H, Wu, F, Zhu, J.
登録日2015-10-27
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
5XIS
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BU of 5xis by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form I
分子名称: E3 ubiquitin-protein ligase RNF168, MAGNESIUM ION, Ubiquitin-40S ribosomal protein S27a, ...
著者Takahashi, T.S, Sato, Y, Fukai, S.
登録日2017-04-27
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
5XIU
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BU of 5xiu by Molmil
Crystal structure of RNF168 UDM2 in complex with Lys63-linked diubiquitin
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase RNF168, Ubiquitin-40S ribosomal protein S27a
著者Takahashi, T.S, Sato, Y, Fukai, S.
登録日2017-04-27
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
1X23
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BU of 1x23 by Molmil
Crystal structure of ubch5c
分子名称: Ubiquitin-conjugating enzyme E2 D3
著者Nakanishi, M, Teshima, N, Mizushima, T, Murata, S, Tanaka, K, Yamane, T.
登録日2005-04-19
公開日2005-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of ubch5c
To be Published
7VZ4
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BU of 7vz4 by Molmil
Cryo-EM structure of human nucleosome core particle composed of the Widom 601L DNA sequence
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Sato, S, Danev, R, Kurumizaka, H.
登録日2021-11-15
公開日2023-05-17
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (1.89 Å)
主引用文献Methods for High Resolution Cryo-EM Analyses of Nucleosomes
To Be Published
6ACL
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BU of 6acl by Molmil
histone lysine desuccinylase Sirt5 in complex with succinyl peptide H2AK95
分子名称: NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION, ...
著者Hang, T.R, Chen, W.B.
登録日2018-07-26
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献complex structure of histone lysine desuccinylase Sirt5 with succinyl peptide H2AK95
To Be Published
8I17
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BU of 8i17 by Molmil
Structural basis for H2A-H2B recognitions by human Spt16
分子名称: CHLORIDE ION, FACT complex subunit SPT16, Histone H2A type 1-B/E, ...
著者Huang, H, Li, Y.
登録日2023-01-12
公開日2023-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for H2A-H2B recognitions by human Spt16.
Biochem.Biophys.Res.Commun., 651, 2023
5B0Z
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BU of 5b0z by Molmil
The crystal structure of the nucleosome containing H3.2, at 1.98 A resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Suzuki, Y, Horikoshi, N, Kato, D, Kurumizaka, H.
登録日2015-11-14
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122
Biochem.Biophys.Res.Commun., 469, 2016
5Y0D
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BU of 5y0d by Molmil
Crystal Structure of the human nucleosome containing the H2B E76K mutant
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
6IPU
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BU of 6ipu by Molmil
Human nucleosome core particle containing 145 bp of DNA
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ...
著者DeFalco, L, Davey, C.A.
登録日2018-11-04
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
4S3O
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BU of 4s3o by Molmil
PCGF5-RING1B-UbcH5c complex
分子名称: E3 ubiquitin-protein ligase RING2, Polycomb group RING finger protein 5, Ubiquitin-conjugating enzyme E2 D3, ...
著者Taherbhoy, A.M, Cochran, A.G.
登録日2015-03-23
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase.
Nat Commun, 6, 2015
8UQA
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BU of 8uqa by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ...
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
5Y0C
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BU of 5y0c by Molmil
Crystal Structure of the human nucleosome at 2.09 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
3L11
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BU of 3l11 by Molmil
Crystal Structure of the Ring Domain of RNF168
分子名称: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
著者Neculai, D, Yermekbayeva, L, Crombet, L, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-12-10
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
8Q3E
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BU of 8q3e by Molmil
High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide
分子名称: DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
5X7X
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BU of 5x7x by Molmil
The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Taguchi, H, Kurumizaka, H.
登録日2017-02-27
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.184 Å)
主引用文献Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
5IFR
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BU of 5ifr by Molmil
Structure of the stable UBE2D3-UbDha conjugate
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3
著者Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D.
登録日2016-02-26
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
5AV9
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BU of 5av9 by Molmil
human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
5AV8
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BU of 5av8 by Molmil
human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
5AV6
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BU of 5av6 by Molmil
human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
5B31
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BU of 5b31 by Molmil
The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1.
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
登録日2016-02-08
公開日2016-08-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
6KE9
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BU of 6ke9 by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-07-04
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
5XIT
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BU of 5xit by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form II
分子名称: E3 ubiquitin-protein ligase RNF168, GLYCEROL, PRASEODYMIUM ION, ...
著者Takahashi, T.S, Sato, Y, Fukai, S.
登録日2017-04-27
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
6JXD
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BU of 6jxd by Molmil
Human nucleosome core particle with cohesive end DNA termini
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者DeFalco, L, Davey, C.A.
登録日2019-04-23
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
6IQ4
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BU of 6iq4 by Molmil
Nucleosome core particle cross-linked with a hetero-binuclear molecule possessing RAPTA and gold(I) 4-(diphenylphosphino)benzoic acid groups.
分子名称: 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ...
著者DeFalco, L, Batchelor, L.K, Adhireksan, Z, Dyson, P.J, Davey, C.A.
登録日2018-11-06
公開日2019-10-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crosslinking Allosteric Sites on the Nucleosome.
Angew.Chem.Int.Ed.Engl., 58, 2019

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件を2024-09-04に公開中

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