5XIU

Crystal structure of RNF168 UDM2 in complex with Lys63-linked diubiquitin

Summary for 5XIU

• Entry DOI: 10.2210/pdb5xiu/pdb
• Related: 5XIS 5XIT
• Descriptor: E3 ubiquitin-protein ligase RNF168, Ubiquitin-40S ribosomal protein S27a, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: ubiquitin, transferase-ribosomal protein complex, transferase/ribosomal protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q8IYW5; Ubiquitin: Cytoplasm : P62983
• Total number of polymer chains: 2
• Total formula weight: 14812.85

Authors

Takahashi, T.S.,Sato, Y.,Fukai, S. (deposition date: 2017-04-27, release date: 2018-03-07, Last modification date: 2023-11-22)

• Primary citation: Takahashi, T.S.,Hirade, Y.,Toma, A.,Sato, Y.,Yamagata, A.,Goto-Ito, S.,Tomita, A.,Nakada, S.,Fukai, S.; Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.; Nat Commun, 9:170-170, 2018; PubMed: 29330428; DOI: 10.1038/s41467-017-02345-y

Experimental method

X-RAY DIFFRACTION (1.8 Å)