Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | LEU436 |
| A | GLU443 |
| A | HOH606 |
| B | HOH203 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| B | GLY35 |
| A | PHE437 |
| A | HIS440 |
| A | LYS441 |
| B | ASP32 |
| B | LYS33 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | LEU453 |
| A | GLU456 |
| A | ASP458 |
| A | HOH603 |
| A | HOH623 |
| B | ARG42 |
| B | VAL70 |
| B | LEU73 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 101 |
| Chain | Residue |
| A | GLU433 |
| A | GLN454 |
| B | THR7 |
| B | LEU8 |
| B | THR9 |
| B | LEU69 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 102 |
| Chain | Residue |
| B | ARG54 |
| B | ASP58 |
| B | TYR59 |
| B | HOH212 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Interacts with activating enzyme |
| Chain | Residue | Details |
| B | ARG54 | |
| B | ARG72 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Essential for function |
| Chain | Residue | Details |
| B | HIS68 | |
| Chain | Residue | Details |
| B | SER65 | |
| Chain | Residue | Details |
| B | GLY76 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P62979 |
| Chain | Residue | Details |
| B | LYS6 | |
| B | LYS11 | |
| B | LYS27 | |
| B | LYS29 | |
| B | LYS33 | |
| B | LYS48 | |
| B | LYS63 | |
| Chain | Residue | Details |
| B | GLY76 | |
