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PDB: 81 件

2X4W
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Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
分子名称: FORMIC ACID, HISTONE H3.2, PEREGRIN
著者Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
登録日2010-02-02
公開日2010-04-21
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
3MO8
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PWWP Domain of Human Bromodomain and PHD finger-containing protein 1 In Complex with Trimethylated H3K36 Peptide
分子名称: Histone H3.2 TRIMETHYLATED H3K36 PEPTIDE, Peregrin
著者Lam, R, Zeng, H, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2010-04-22
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
4MZG
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Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
著者Su, X, Ding, X, Li, H.
登録日2013-09-30
公開日2014-03-26
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
2X4Y
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Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
分子名称: HISTONE H3.2, PEREGRIN, SULFATE ION
著者Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
登録日2010-02-02
公開日2010-04-21
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4X
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BU of 2x4x by Molmil
Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
分子名称: HISTONE H3.2, PEREGRIN, SULFATE ION
著者Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
登録日2010-02-02
公開日2010-04-21
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
4OUC
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Structure of human haspin in complex with histone H3 substrate
分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 1,2-ETHANEDIOL, Histone H3.2, ...
著者Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2014-02-15
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modulation of the chromatin phosphoproteome by the haspin protein kinase.
Mol Cell Proteomics, 13, 2014
5VAC
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Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide
分子名称: DIMETHYL SULFOXIDE, Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, ...
著者Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.F.
登録日2017-03-24
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
7UVA
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BU of 7uva by Molmil
Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide modified by UNC8015
分子名称: FE (III) ION, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Budziszewski, G.R, Azzam, D.N, Spangler, C.J, Skrajna, A, Foley, C.A, James, L.I, Frye, S.V, McGinty, R.K.
登録日2022-04-29
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
6ACE
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BU of 6ace by Molmil
histone lysine desuccinylase Sirt5 in complex with succinyl peptide H3K122
分子名称: GLYCEROL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ...
著者Hang, T.R, Chen, W.B.
登録日2018-07-26
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献complex structure of histone lysine desuccinylase Sirt5 with succinyl peptide H3K122
To Be Published
5B0Z
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The crystal structure of the nucleosome containing H3.2, at 1.98 A resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Suzuki, Y, Horikoshi, N, Kato, D, Kurumizaka, H.
登録日2015-11-14
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122
Biochem.Biophys.Res.Commun., 469, 2016
3R93
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BU of 3r93 by Molmil
Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
分子名称: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION
著者Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC)
登録日2011-03-24
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
4MZF
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BU of 4mzf by Molmil
Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide
分子名称: CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ...
著者Su, X, Ding, X, Li, H.
登録日2013-09-30
公開日2014-03-26
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
4MZH
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BU of 4mzh by Molmil
Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2s) peptide
分子名称: MAGNESIUM ION, Peptide from Histone H3.2, Spindlin-1
著者Su, X, Ding, X, Li, H.
登録日2013-09-30
公開日2014-03-26
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
5CIU
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BU of 5ciu by Molmil
Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain
分子名称: DNA (cytosine-5)-methyltransferase 3B, GLYCEROL, Histone H3.2
著者Rondelet, G, DAL MASO, T, Willems, L, Wouters, J.
登録日2015-07-13
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
J.Struct.Biol., 194, 2016
8JLB
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BU of 8jlb by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
3DB3
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BU of 3db3 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide
著者Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-09-16
最終更新日2012-04-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
8JLD
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BU of 8jld by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
3AV1
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BU of 3av1 by Molmil
The human nucleosome structure containing the histone variant H3.2
分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H.
登録日2011-02-18
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
5B0Y
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Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Suzuki, Y, Horikoshi, N, Kurumizaka, H.
登録日2015-11-13
公開日2016-01-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.557 Å)
主引用文献Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122
Biochem.Biophys.Res.Commun., 469, 2016
7XCR
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BU of 7xcr by Molmil
Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex
分子名称: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-25
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7XCT
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BU of 7xct by Molmil
Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex
分子名称: DNA (145-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-25
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
5BO0
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Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer
分子名称: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.2, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
6X59
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The mouse cGAS catalytic domain binding to human assembled nucleosome
分子名称: Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ...
著者Pengbiao, X, Pingwei, L, Baoyu, Z.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
7TAN
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Structure of VRK1 C-terminal tail bound to nucleosome core particle
分子名称: Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, Histone H3.2, ...
著者Spangler, C.J, Budziszewski, G.R, McGinty, R.K.
登録日2021-12-21
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.
Nucleic Acids Res., 50, 2022
8HR1
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Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L.
登録日2022-12-14
公開日2023-09-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024

 

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