4V8E
| Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V5C
| Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA. | 分子名称: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-03-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome Nat.Struct.Mol.Biol., 16, 2009
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4V8C
| Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V7J
| Structure of RelE nuclease bound to the 70S ribosome (precleavage state) | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | 登録日 | 2009-11-02 | 公開日 | 2014-07-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
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4WZO
| Complex of 70S ribosome with tRNA-fMet and mRNA | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-11-20 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4WSM
| Complex of 70S ribosome with tRNA-Leu and mRNA with G-U mismatch in the first position in the A- and P-sites | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-28 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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7AZO
| 70S thermus thermophilus ribosome with bound antibiotic lead SEQ-977 | 分子名称: | (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,4R,6R)-3-hydroxy-4-(methoxyamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-((2-nitrophenyl)sulfonamido)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... | 著者 | Jenner, L.B, Yusupov, M, Yusupova, G. | 登録日 | 2020-11-17 | 公開日 | 2022-06-01 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
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5VPO
| The 70S P-site ASL SufA6 complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2017-05-05 | 公開日 | 2018-09-26 | 最終更新日 | 2018-11-07 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4V8X
| Structure of Thermus thermophilus ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Feng, S, Chen, Y, Kamada, K, Wang, H, Tang, K, Wang, M, Gao, Y.G. | 登録日 | 2013-07-19 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Yoeb-Ribosome Structure: A Canonical Rnase that Requires the Ribosome for its Specific Activity. Nucleic Acids Res., 41, 2013
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6GSK
| Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Yusupov, M, Yusupova, G. | 登録日 | 2018-06-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
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6NSH
| Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | 登録日 | 2019-01-24 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.397 Å) | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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4WT8
| Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex | 分子名称: | 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Amunts, A, Fiedorczuk, K, Ramakrishnan, V. | 登録日 | 2014-10-29 | 公開日 | 2015-01-21 | 最終更新日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
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4YPB
| Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2015-03-12 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
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1VVJ
| Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | 登録日 | 2013-05-24 | 公開日 | 2014-08-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.440001 Å) | 主引用文献 | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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4V5E
| Insights into translational termination from the structure of RF2 bound to the ribosome | 分子名称: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-04-30 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome. Science, 322, 2008
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4V7M
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4LSK
| Crystal Structure of tRNA Proline (CGG) Bound to Codon CCG-G on the Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | 登録日 | 2013-07-22 | 公開日 | 2014-08-06 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.48000622 Å) | 主引用文献 | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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6OXI
| Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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4V5A
| Structure of the Ribosome Recycling Factor bound to the Thermus thermophilus 70S ribosome with mRNA, ASL-Phe and tRNA-fMet | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Weixlbaumer, A, Petry, S, Dunham, C.M, Selmer, M, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2007-06-28 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the ribosome recycling factor bound to the ribosome. Nat. Struct. Mol. Biol., 14, 2007
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4V5D
| Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA. | 分子名称: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-03-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome. Nat. Struct. Mol. Biol., 16, 2009
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4V6G
| Initiation complex of 70S ribosome with two tRNAs and mRNA. | 分子名称: | 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Jenner, L.B, Yusupova, G, Yusupov, M. | 登録日 | 2009-07-10 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat.Struct.Mol.Biol., 17, 2010
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6UCQ
| Crystal structure of the Thermus thermophilus 70S ribosome recycling complex | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J. | 登録日 | 2019-09-17 | 公開日 | 2019-12-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for ribosome recycling by RRF and tRNA. Nat.Struct.Mol.Biol., 27, 2020
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6NWY
| Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-02-07 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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6QNQ
| 70S ribosome initiation complex (IC) with experimentally assigned potassium ions | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G. | 登録日 | 2019-02-11 | 公開日 | 2019-06-19 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction. Nat Commun, 10, 2019
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6BUW
| Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | 登録日 | 2017-12-11 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Res., 47, 2019
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