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PDB: 1180 件

3U0P
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Crystal structure of human CD1d-lysophosphatidylcholine
分子名称: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J.
登録日2011-09-28
公開日2012-04-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
3AM8
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Crystal Structure of a Human Major Histocompatibilty complex
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Chacko, J, Clements, C, Rossjohn, J.
登録日2010-08-18
公開日2011-08-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a Human Major Histocompatibility complex
To be Published
4JRY
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Crystal Structure of SB47 TCR-HLA B*3505-LPEP complex
分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2013-03-22
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule.
J.Biol.Chem., 288, 2013
1QSF
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STRUCTURE OF A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE Y8A
分子名称: BETA-2 MICROGLOBULIN, HUMAN T-CELL RECEPTOR, MHC CLASS I HLA-A, ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-21
公開日1999-12-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
1QRN
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CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A
分子名称: BETA-2 MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-14
公開日1999-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
3GSN
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BU of 3gsn by Molmil
Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope
分子名称: Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ...
著者Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
1GZP
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CD1b in complex with GM2 ganglioside
分子名称: B2-MICROGLOBULIN, DOCOSANE, DODECANE, ...
著者Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
登録日2002-05-24
公開日2002-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
3QDM
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The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide
分子名称: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-18
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
8SGB
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.80001545 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
3JTS
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GY9-Mamu-A*02-hb2m
分子名称: Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Gag-Pol polyprotein
著者Dai, L, Feng, Y, Qi, J, Gao, G.F.
登録日2009-09-14
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structure of Mamu A*2
To be Published
6EQB
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HLA class I histocompatibility antigen
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2017-10-12
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献TCR-induced alteration of primary MHC peptide anchor residue.
Eur.J.Immunol., 49, 2019
7N1B
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BU of 7n1b by Molmil
SARS-CoV-2 RLQ peptide binds to HLA-A2
分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
著者Wu, D, Mariuzza, R.A.
登録日2021-05-27
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
5MEN
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Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
3D39
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The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
登録日2008-05-09
公開日2009-06-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
Biochem.J., 423, 2009
7RE8
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BU of 7re8 by Molmil
Class I MHC (HLA-A*02) presenting alpha fetoprotein peptide (AFP)
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, MHC class I antigen, ...
著者Dasgupta, M, Baker, B.M.
登録日2021-07-12
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
6LA7
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BU of 6la7 by Molmil
Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5
分子名称: Beta-2-microglobulin, Capsid protein VP1, Capsid protein VP2, ...
著者Liu, S, Gao, F.G.
登録日2019-11-12
公開日2020-10-07
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn.
Chin.Sci.Bull., 2020
4PJB
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BU of 4pjb by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
6VMC
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BU of 6vmc by Molmil
T4H2 T cell receptor bound to HLA-A2 presenting gp100T2L peptide (ILDQVPFSV)
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Smith, A.R, Baker, B.M.
登録日2020-01-27
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner
Proc.Natl.Acad.Sci.USA, 118, 2021
5WJN
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BU of 5wjn by Molmil
Crystal Structure of HLA-A*11:01-GTS3
分子名称: Beta-2-microglobulin, GTS3 peptide, HLA class I histocompatibility antigen, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-23
公開日2017-09-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
1MHE
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BU of 1mhe by Molmil
THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ...
著者O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y.
登録日1998-08-24
公開日1999-03-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
5BXF
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BU of 5bxf by Molmil
Apo FcRn Structure at pH 4.5
分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51
著者Nam, H.-J, Taha, M.
登録日2015-06-08
公開日2015-11-11
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Human Fc-Receptor Neonatal at low pH gives insights into different states of FcRn
To Be Published
8HN4
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BU of 8hn4 by Molmil
Complex structure of HLA2402 with recognizing SARS-CoV-2 epitope QYIKWPWYI
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 T-cell epitope QYIKWPWYI
著者Deng, S.S, Jin, T.C, Xu, Z.H.
登録日2022-12-07
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Immune escape at SARS- CoV-2 killer T cell epitope
To be published
8U9G
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Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
登録日2023-09-19
公開日2024-01-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
4LHU
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Crystal Structure of 9C2 TCR bound to CD1d
分子名称: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I.
登録日2013-07-01
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献CD1d-lipid antigen recognition by the gamma delta TCR.
Nat.Immunol., 14, 2013
5V5M
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Crystal structure of HLA-B*5701 complex with HIV-1 gag derived peptide TW10
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Li, X, Wang, J.-H.
登録日2017-03-14
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.
Cell. Mol. Immunol., 14, 2017

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