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PDB: 1180 件

3UPR
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HLA-B*57:01 complexed to pep-V and Abacavir
分子名称: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
著者Pompeu, Y.A, Ostrov, D.A.
登録日2011-11-18
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proc.Natl.Acad.Sci.USA, 109, 2012
7MXF
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BU of 7mxf by Molmil
CD1c with antigen analogue 2
分子名称: (2S)-2,3-dihydroxypropyl hexadecanoate, 2,6-anhydro-1-deoxy-1-[(S)-hydroxy{[(4R,8S,12R,16R,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
著者Cao, T.P, Shahine, A, Rossjohn, J.
登録日2021-05-19
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
J.Biol.Chem., 297, 2021
1LP9
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Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J.
登録日2002-05-07
公開日2003-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.
Immunity, 19, 2003
3LKR
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BU of 3lkr by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 2009 H1N1 swine origin strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
2BSS
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BU of 2bss by Molmil
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705
分子名称: BETA-2-MICROGLOBULIN, HIV PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN
著者Stewart-Jones, G.B.E, Di Gleria, K, Kollnberger, S, Mcmichael, A.J, Jones, E.Y, Bowness, P.
登録日2005-05-23
公開日2005-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
3DBX
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BU of 3dbx by Molmil
Structure of chicken CD1-2 with bound fatty acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CD1-2 antigen, ...
著者Zajonc, D.M, Wilson, I.A.
登録日2008-06-02
公開日2008-11-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1
Proc.Natl.Acad.Sci.Usa, 105, 2008
5VWJ
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BU of 5vwj by Molmil
HLA-B*58:01 presenting LTVQVARVW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-22
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3DHJ
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BU of 3dhj by Molmil
Beta 2 microglobulin mutant W60C
分子名称: Beta-2-microglobulin
著者Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
登録日2008-06-18
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
1A1N
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BU of 1a1n by Molmil
MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, ...
著者Smith, K.J, Reid, S.W, Stuart, D.I, Mcmichael, A.J, Jones, E.Y, Bell, J.I.
登録日1997-12-11
公開日1998-04-08
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Immunity, 4, 1996
4NQX
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Crystal Structure of HLA A*0101 in complex with NP44-S7N, an 9-mer influenza epitope
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-1 alpha chain, ...
著者Rossjohn, J, Gras, S.
登録日2013-11-26
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
Proc.Natl.Acad.Sci.USA, 111, 2014
8GLF
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BU of 8glf by Molmil
Crystal Structure of Human CD1b in Complex with Sphingomyelin C34:2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Shahine, A.
登録日2023-03-22
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
4NO2
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BU of 4no2 by Molmil
Crystal structure of RQA_V phosphopeptide bound to HLA-A2
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
2X70
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BU of 2x70 by Molmil
Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
著者Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
登録日2010-02-22
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals.
J.Am.Chem.Soc., 131, 2009
6J1V
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BU of 6j1v by Molmil
The structure of HLA-A*3003/RT313
分子名称: Beta-2-microglobulin, HLA-A*3003, RT313
著者Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J.
登録日2018-12-29
公開日2019-09-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides.
Front Immunol, 10, 2019
7SH4
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BU of 7sh4 by Molmil
CD1a-phosphatidylglycerol binary structure
分子名称: (21R,24R,27S)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Wegrecki, M, Rossjohn, J.
登録日2021-10-07
公開日2022-10-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
Nat.Immunol., 24, 2023
7DYN
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BU of 7dyn by Molmil
Phosphorylation of MHC I peptide
分子名称: ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen
著者Sun, M.W, Feng, L, Qi, J.X, Liu, W.J.
登録日2021-01-22
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules.
Iscience, 25, 2022
4LNR
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BU of 4lnr by Molmil
The structure of HLA-B*35:01 in complex with the peptide (RPQVPLRPMTY)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Cheng, H, Shi, Y, Qi, J, Gao, G.F.
登録日2013-07-12
公開日2014-07-23
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.
J.Biol.Chem., 289, 2014
5U16
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BU of 5u16 by Molmil
Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR
分子名称: 2-hydroxynaphthalene-1-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ...
著者Keller, A.N, Birkinshaw, R.W, Rossjohn, J.
登録日2016-11-27
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
6C97
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BU of 6c97 by Molmil
Crystal structure of FcRn at pH3
分子名称: Beta-2-microglobulin, GLYCEROL, IgG receptor FcRn large subunit p51
著者Fox III, D, Fairman, J.W.
登録日2018-01-25
公開日2018-05-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
2BVQ
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BU of 2bvq by Molmil
Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression
分子名称: BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y.
登録日2005-07-01
公開日2005-09-07
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
6VB3
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BU of 6vb3 by Molmil
HLA-B*15:01 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HLA-B*15:01 complexed with a synthetic peptide
To Be Published
4L4T
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BU of 4l4t by Molmil
Structure of human MAIT TCR in complex with human MR1-6-FP
分子名称: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ...
著者Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
登録日2013-06-09
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
6C99
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Crystal structure of FcRn bound to UCB-303
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CITRIC ACID, ...
著者Fox III, D, Abendroth, J, Porter, J, Deboves, H.
登録日2018-01-25
公開日2018-05-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
3KPN
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BU of 3kpn by Molmil
Crystal Structure of HLA B*4403 in complex with EEYLQAFTY a self peptide from the ABCD3 protein
分子名称: Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
4PJH
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BU of 4pjh by Molmil
Structure of human MR1-Ac-6-FP in complex with human MAIT B-G8 TCR
分子名称: Beta-2-microglobulin, GLYCEROL, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014

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