3Q6N
 
 | | Crystal Structure of Human MC-HSP90 in P21 space group | | 分子名称: | Heat shock protein HSP 90-alpha, SULFATE ION | | 著者 | Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J. | | 登録日 | 2011-01-03 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | The hexameric structures of human heat shock protein 90
Plos One, 6, 2011
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7L7J
 | | Cryo-EM structure of Hsp90:p23 closed-state complex | | 分子名称: | Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Prostaglandin E synthase 3 | | 著者 | Lee, K, Thwin, A.C, Tse, E, Gates, S.N, Southworth, D.R. | | 登録日 | 2020-12-28 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.
Mol.Cell, 81, 2021
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2QF6
 | | HSP90 complexed with A56322 | | 分子名称: | 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE, Heat shock protein HSP 90-alpha | | 著者 | Park, C.H. | | 登録日 | 2007-06-26 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Chem.Biol.Drug Des., 70, 2007
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7RXZ
 | | human Hsp90_MC domain structure | | 分子名称: | Heat shock protein HSP 90-alpha | | 著者 | Peng, S, Deng, J, Matts, R. | | 登録日 | 2021-08-24 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.152 Å) | | 主引用文献 | Structural basis of the key residue W320 responsible for Hsp90 conformational change.
J.Biomol.Struct.Dyn., 2022
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8FFW
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2C2L
 | | Crystal structure of the CHIP U-box E3 ubiquitin ligase | | 分子名称: | CARBOXY TERMINUS OF HSP70-INTERACTING PROTEIN, HSP90, NICKEL (II) ION, ... | | 著者 | Zhang, M, Roe, S.M, Pearl, L.H. | | 登録日 | 2005-09-29 | | 公開日 | 2005-11-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Chaperoned Ubiquitylation-Crystal Structures of the Chip U Box E3 Ubiquitin Ligase and a Chip-Ubc13-Uev1A Complex
Mol.Cell, 20, 2005
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7L7I
 | | Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex | | 分子名称: | Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Peptidyl-prolyl cis-trans isomerase FKBP5, ... | | 著者 | Lee, K, Thwin, A.C, Tse, E, Gates, S.N, Southworth, D.R. | | 登録日 | 2020-12-28 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.
Mol.Cell, 81, 2021
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7RY1
 | | human Hsp90_MC domain structure | | 分子名称: | Heat shock protein HSP 90-alpha, N-[2-(1-MALEIMIDYL)ETHYL]-7-DIETHYLAMINOCOUMARIN-3-CARBOXAMIDE | | 著者 | Peng, S, Deng, J, Matts, R. | | 登録日 | 2021-08-24 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.523 Å) | | 主引用文献 | Crystal structure of the middle and C-terminal domains of Hsp90 alpha labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target.
Acta Crystallogr D Struct Biol, 78, 2022
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7KW7
 | | Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... | | 著者 | Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. | | 登録日 | 2020-11-30 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Nature, 601, 2022
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2BUG
 | | Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived peptide | | 分子名称: | HSP90, SERINE/THREONINE PROTEIN PHOSPHATASE 5 | | 著者 | Cliff, M.J, Harris, R, Barford, D, Ladbury, J.E, Williams, M.A. | | 登録日 | 2005-06-13 | | 公開日 | 2006-03-16 | | 最終更新日 | 2020-01-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14, 2006
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6FDP
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8B7I
 | | Human HSP90 alpha ATP Binding Domain, ATP-lid open conformation, R60A | | 分子名称: | HSP90AA1 protein | | 著者 | Rioual, E, Henot, F, Favier, A, Macek, P, Crublet, E, Josso, P, Brutscher, B, Frech, M, Gans, P, Loison, C, Boisbouvier, J. | | 登録日 | 2022-09-30 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Visualizing the transiently populated closed-state of human HSP90 ATP binding domain.
Nat Commun, 13, 2022
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8B7J
 | | Human HSP90 alpha ATP Binding Domain, ATP-lid closed conformation, R46A | | 分子名称: | HSP90AA1 protein | | 著者 | Rioual, E, Henot, F, Favier, A, Macek, P, Crublet, E, Josso, P, Brustcher, B, Frech, M, Gans, P, Loison, C, Boisbouvier, J. | | 登録日 | 2022-09-30 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Visualizing the transiently populated closed-state of human HSP90 ATP binding domain.
Nat Commun, 13, 2022
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2K5B
 | | Human CDC37-HSP90 docking model based on NMR | | 分子名称: | Heat shock protein HSP 90-alpha, Hsp90 co-chaperone Cdc37 | | 著者 | Sreeramulu, S, Jonker, H.R.A, Lancaster, C.R, Richter, C, Langer, T, Schwalbe, H. | | 登録日 | 2008-06-26 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy
J.Biol.Chem., 284, 2009
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