7L7J

Cryo-EM structure of Hsp90:p23 closed-state complex

Summary for 7L7J

• Entry DOI: 10.2210/pdb7l7j/pdb
• Related: 7L7I
• EMDB information: 23213 23214
• Descriptor: Prostaglandin E synthase 3, Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
• Functional Keywords: chaperone
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 189296.24

Authors

Lee, K.,Thwin, A.C.,Tse, E.,Gates, S.N.,Southworth, D.R. (deposition date: 2020-12-28, release date: 2021-08-25, Last modification date: 2024-05-29)

• Primary citation: Lee, K.,Thwin, A.C.,Nadel, C.M.,Tse, E.,Gates, S.N.,Gestwicki, J.E.,Southworth, D.R.; The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.; Mol.Cell, 81:3496-, 2021; PubMed: 34380015; DOI: 10.1016/j.molcel.2021.07.023

Experimental method

ELECTRON MICROSCOPY (3.1 Å)