2K5B

Human CDC37-HSP90 docking model based on NMR

Summary for 2K5B

• Entry DOI: 10.2210/pdb2k5b/pdb
• Related: 1YES
• Descriptor: Heat shock protein HSP 90-alpha, Hsp90 co-chaperone Cdc37 (2 entities in total)
• Functional Keywords: cdc37, hsp90, protein-protein interaction, heat shock protein, p50, alternative splicing, atp-binding, chaperone, cytoplasm, nucleotide-binding, phosphoprotein, stress response, polymorphism
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P07900 Q16543
• Total number of polymer chains: 2
• Total formula weight: 39056.67

Authors

Sreeramulu, S.,Jonker, H.R.A.,Lancaster, C.R.,Richter, C.,Langer, T.,Schwalbe, H. (deposition date: 2008-06-26, release date: 2008-12-09, Last modification date: 2022-03-16)

• Primary citation: Sreeramulu, S.,Jonker, H.R.A.,Langer, T.,Richter, C.,Lancaster, C.R.,Schwalbe, H.; The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy; J.Biol.Chem., 284:3885-3896, 2009; PubMed: 19073599; DOI: 10.1074/jbc.M806715200

Experimental method

SOLUTION NMR