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PDB: 17 件
4V0P
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BU of 4v0p by Molmil
Crystal structure of the MAGE homology domain of human MAGE-A3
分子名称: MELANOMA-ASSOCIATED ANTIGEN 3
著者Newman, J.A, Aitkenhead, H, Cooper, C.D.O, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2014-09-17
公開日2014-10-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
6WJH
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BU of 6wjh by Molmil
Crystal structure of MAGE-A11 bound to the PCF11 degron
分子名称: Fusion protein of PCF11 and MAGE-A11
著者Miller, D.J, Huang, X.
登録日2020-04-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Nat Commun, 11, 2020
2WA0
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BU of 2wa0 by Molmil
Crystal structure of the human MAGEA4
分子名称: MELANOMA-ASSOCIATED ANTIGEN 4
著者Roos, A.K, Cooper, C.D.O, Ugochukwu, E, W Yue, W, Berridge, G, Elkins, J.M, Pike, A.C.W, Bray, J, Filippakopoulos, P, Muniz, J, Chaikuad, A, Burgess-Brown, N, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O, Oppermann, U.
登録日2009-01-31
公開日2009-03-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
6R7T
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BU of 6r7t by Molmil
Crystal Structure of human Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
分子名称: Melanoma-associated antigen B1, anti MAGEB1 nanobody
著者Ye, M, Newman, J, Pike, A.C.W, Burgess-Brown, N, Cooper, C.D.O, Bountra, C, Arrowsmith, C, Edwards, A, Gileadi, O, von Delft, F.
登録日2019-03-29
公開日2019-05-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献Crystal Structure of Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
To Be Published
9BD3
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BU of 9bd3 by Molmil
Structure of the MAGEA4 MHD-RAD18 R6BD Complex
分子名称: E3 ubiquitin-protein ligase RAD18, Melanoma antigen A 4
著者Forker, K, Zhou, P.
登録日2024-04-10
公開日2024-06-05
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of MAGEA4 MHD-RAD18 R6BD reveals a flipped binding mode compared to AlphaFold2 prediction.
Embo J., 2024
7UOA
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BU of 7uoa by Molmil
MAGEA4-MTP1 linear peptide complex
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MTP-1, ...
著者Williams, R.S, Tumbale, P.S.
登録日2022-04-12
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
J.Med.Chem., 65, 2022
8I13
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BU of 8i13 by Molmil
Cryo-EM structure of 6-subunit Smc5/6
分子名称: MMS21 isoform 1, NSE3 isoform 1, Non-structural maintenance of chromosomes element 1 homolog, ...
著者Qian, L, Jun, Z, Xiang, Z, Cheng, T, Zhaoning, W, Duo, J, Zhenguo, C, Wang, L.
登録日2023-01-12
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
7DG2
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BU of 7dg2 by Molmil
Nse1-Nse3-Nse4 complex
分子名称: ACETATE ION, GLYCEROL, MAGE domain-containing protein, ...
著者Cho, Y, Jo, A.
登録日2020-11-10
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.
J.Mol.Biol., 433, 2021
7QCD
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BU of 7qcd by Molmil
CryoEM structure of the Smc5/6-holocomplex (composite structure)
分子名称: E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, ...
著者Hallett, S.T, Oliver, A.W.
登録日2021-11-23
公開日2022-09-21
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Cryo-EM structure of the Smc5/6 holo-complex.
Nucleic Acids Res., 50, 2022
8HQS
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BU of 8hqs by Molmil
Cryo-EM structure of 8-subunit Smc5/6 head region
分子名称: DNA repair protein KRE29, Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, ...
著者Qian, L, Jun, Z, Xiang, Z, Tong, C, Wang, Z, Duo, J, Zhenguo, C, Wang, L.
登録日2022-12-14
公開日2024-06-19
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
5WY5
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BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
分子名称: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
著者Yang, M, Gao, J.
登録日2017-01-11
公開日2017-05-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
5HVQ
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BU of 5hvq by Molmil
Alternative model of the MAGE-G1 NSE-1 complex
分子名称: Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ZINC ION
著者Newman, J.A, Cooper, C.D.O, Roos, A.K, Aitkenhead, H, Oppermann, U.C.T, Cho, H.J, Osman, R, Gileadi, O.
登録日2016-01-28
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.923 Å)
主引用文献Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
8WJN
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BU of 8wjn by Molmil
Cryo-EM structure of 6-subunit Smc5/6 head region
分子名称: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosomes element 1, Non-structural maintenance of chromosomes element 4, ...
著者Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.58 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
7YMD
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BU of 7ymd by Molmil
Cryo-EM structure of Nse1/3/4
分子名称: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosomes element 1
著者Qian, L, Jun, Z, Zhenguo, C, Wang, L.
登録日2022-07-28
公開日2024-01-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.176 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
7YQH
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BU of 7yqh by Molmil
Cryo-EM structure of 8-subunit Smc5/6
分子名称: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, ...
著者Qian, L, Jun, Z, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W.
登録日2022-08-07
公開日2024-01-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
7TVE
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BU of 7tve by Molmil
ATP and DNA bound SMC5/6 core complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ...
著者Yu, Y, Patel, D.J.
登録日2022-02-04
公開日2022-06-22
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Proc.Natl.Acad.Sci.USA, 119, 2022
8T9A
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BU of 8t9a by Molmil
CryoEM structure of human DDB1-DCAF12 in complex with MAGEA3
分子名称: DDB1- and CUL4-associated factor 12, DNA damage-binding protein 1, Melanoma-associated antigen 3
著者Duda, D, Righetto, G, Li, Y, Loppnau, P, Seitova, A, Santhakumar, V, Halabelian, L, Yin, Y.
登録日2023-06-23
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献CryoEM structure of human DDB1-DCAF12 in complex with MAGEA3
To Be Published

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件を2024-07-17に公開中

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