7UOA

MAGEA4-MTP1 linear peptide complex

Summary for 7UOA

• Entry DOI: 10.2210/pdb7uoa/pdb
• Descriptor: Melanoma antigen A 4, MTP-1, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: mage homology domain mhd, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 26543.23

Authors

Williams, R.S.,Tumbale, P.S. (deposition date: 2022-04-12, release date: 2022-09-07, Last modification date: 2023-10-18)

• Primary citation: Fleming, M.C.,Chiou, L.F.,Tumbale, P.P.,Droby, G.N.,Lim, J.,Norris-Drouin, J.L.,Williams, J.G.,Pearce, K.H.,Williams, R.S.,Vaziri, C.,Bowers, A.A.; Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.; J.Med.Chem., 65:7231-7245, 2022; PubMed: 35522528; DOI: 10.1021/acs.jmedchem.2c00185

Experimental method

X-RAY DIFFRACTION (3.5 Å)