6WJH
Crystal structure of MAGE-A11 bound to the PCF11 degron
Summary for 6WJH
Entry DOI | 10.2210/pdb6wjh/pdb |
Descriptor | Fusion protein of PCF11 and MAGE-A11 (2 entities in total) |
Functional Keywords | mage-a11, pcf 11, ubiquitin ligase, protein complex, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 111203.29 |
Authors | Miller, D.J.,Huang, X. (deposition date: 2020-04-13, release date: 2020-10-14, Last modification date: 2023-10-18) |
Primary citation | Yang, S.W.,Huang, X.,Lin, W.,Min, J.,Miller, D.J.,Mayasundari, A.,Rodrigues, P.,Griffith, E.C.,Gee, C.T.,Li, L.,Li, W.,Lee, R.E.,Rankovic, Z.,Chen, T.,Potts, P.R. Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nat Commun, 11:4931-4931, 2020 Cited by PubMed: 33004795DOI: 10.1038/s41467-020-18708-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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