6WJH

Crystal structure of MAGE-A11 bound to the PCF11 degron

Summary for 6WJH

Entry DOI	10.2210/pdb6wjh/pdb
Descriptor	Fusion protein of PCF11 and MAGE-A11 (2 entities in total)
Functional Keywords	mage-a11, pcf 11, ubiquitin ligase, protein complex, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	111203.29
Authors	Miller, D.J.,Huang, X. (deposition date: 2020-04-13, release date: 2020-10-14, Last modification date: 2023-10-18)
Primary citation	Yang, S.W.,Huang, X.,Lin, W.,Min, J.,Miller, D.J.,Mayasundari, A.,Rodrigues, P.,Griffith, E.C.,Gee, C.T.,Li, L.,Li, W.,Lee, R.E.,Rankovic, Z.,Chen, T.,Potts, P.R. Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nat Commun, 11:4931-4931, 2020 Cited by PubMed: 33004795 DOI: 10.1038/s41467-020-18708-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation