2WA0

Crystal structure of the human MAGEA4

Summary for 2WA0

• Entry DOI: 10.2210/pdb2wa0/pdb
• Related: 1I4F
• Descriptor: MELANOMA-ASSOCIATED ANTIGEN 4 (2 entities in total)
• Functional Keywords: immune system, multiple anomalous dispersion, cancer/testis antigen 1.4, melanoma antigen family a 4, ct1.4, mage-41, mage-x2, tumor antigen, melanoma-associated antigen 4
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 27415.18

Authors

Roos, A.K.,Cooper, C.D.O.,Ugochukwu, E.,W Yue, W.,Berridge, G.,Elkins, J.M.,Pike, A.C.W.,Bray, J.,Filippakopoulos, P.,Muniz, J.,Chaikuad, A.,Burgess-Brown, N.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,von Delft, F.,Gileadi, O.,Oppermann, U. (deposition date: 2009-01-31, release date: 2009-03-10, Last modification date: 2018-01-24)

• Primary citation: Newman, J.A.,Cooper, C.D.O.,Roos, A.K.,Aitkenhead, H.,Oppermann, U.C.T.,Cho, H.J.,Osman, R.,Gileadi, O.; Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.; Plos One, 11:48762-, 2016; PubMed: 26910052; DOI: 10.1371/JOURNAL.PONE.0148762

Experimental method

X-RAY DIFFRACTION (2.3 Å)