9BD3

Structure of the MAGEA4 MHD-RAD18 R6BD Complex

Summary for 9BD3

• Entry DOI: 10.2210/pdb9bd3/pdb
• Descriptor: Melanoma antigen A 4, E3 ubiquitin-protein ligase RAD18 (3 entities in total)
• Functional Keywords: rad18, magea4, tls, cell cycle, e3
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 56706.89

Authors

Forker, K.,Zhou, P. (deposition date: 2024-04-10, release date: 2024-06-05, Last modification date: 2024-07-24)

Primary citation

Forker, K.,Fleming, M.C.,Pearce, K.H.,Vaziri, C.,Bowers, A.A.,Zhou, P.
Crystal structure of MAGEA4 MHD-RAD18 R6BD reveals a flipped binding mode compared to AlphaFold2 prediction.
Embo J., 43:2835-2839, 2024

PubMed Abstract: [Image: see text]

PubMed: 38907034
DOI: 10.1038/s44318-024-00140-2

Experimental method

X-RAY DIFFRACTION (2.58 Å)