Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 592 件
6N6T
DownloadVisualize
BU of 6n6t by Molmil
OXA-23 mutant F110A/M221A low pH form
分子名称: Beta-lactamase oxa23, CITRATE ANION
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6Y
DownloadVisualize
BU of 6n6y by Molmil
OXA-23 mutant F110A/M221A neutral pH form meropenem complex
分子名称: Beta-lactamase oxa23, meropenem, bound form
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6NLW
DownloadVisualize
BU of 6nlw by Molmil
The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
分子名称: Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Tan, K, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-09
公開日2019-01-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
To Be Published
6NHU
DownloadVisualize
BU of 6nhu by Molmil
Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, GLYCEROL, ...
著者Kim, Y, Welk, L, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-23
公開日2019-01-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
To Be Published
6NHS
DownloadVisualize
BU of 6nhs by Molmil
Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Kim, Y, Tesar, C, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-23
公開日2019-01-16
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
To Be Published
6NZ8
DownloadVisualize
BU of 6nz8 by Molmil
Structure of carbamylated apo OXA-231 carbapenemase
分子名称: Beta-lactamase OXA-231, CHLORIDE ION, SODIUM ION
著者Favaro, D.C, Llontop, E.E, Vasconcelos, F.N, Antunes, V.U, Farah, S.C, Lincopan, N.
登録日2019-02-13
公開日2020-02-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Importance of the beta 5-beta 6 Loop for the Structure, Catalytic Efficiency, and Stability of Carbapenem-Hydrolyzing Class D beta-Lactamase Subfamily OXA-143.
Biochemistry, 58, 2019
6O9S
DownloadVisualize
BU of 6o9s by Molmil
Crystal structure of Staphylococcus aureus MecR1 antibiotic-sensor domain in complex with avibactam
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Methicillin resistance mecR1 protein, SULFATE ION
著者Alexander, J.A.N, Strynadka, N.C.J.
登録日2019-03-14
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus .
J.Biol.Chem., 295, 2020
6O9W
DownloadVisualize
BU of 6o9w by Molmil
Crystal structure of Staphylococcus aureus BlaR1 antibiotic-sensor domain in complex with avibactam
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Regulatory protein BlaR1
著者Alexander, J.A.N, Strynadka, N.C.J.
登録日2019-03-15
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus .
J.Biol.Chem., 295, 2020
6N6U
DownloadVisualize
BU of 6n6u by Molmil
OXA-23 mutant F110A/M221A low pH form imipenem complex
分子名称: Beta-lactamase, Imipenem
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6X
DownloadVisualize
BU of 6n6x by Molmil
OXA-23 mutant F110A/M221A neutral pH form imipenem complex
分子名称: Beta-lactamase oxa23, Imipenem, SULFATE ION
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6P56
DownloadVisualize
BU of 6p56 by Molmil
Crystal structure of the transpeptidase domain of a T498A mutant of PBP2 from Neisseria gonorrhoeae
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P52
DownloadVisualize
BU of 6p52 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae with a bound phosphate at the active site
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P96
DownloadVisualize
BU of 6p96 by Molmil
OXA-48 carbapanemase, apo form
分子名称: Beta-lactamase, CADMIUM ION, CALCIUM ION, ...
著者Smith, C.A, Vakulenko, S.B.
登録日2019-06-10
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.
Antimicrob.Agents Chemother., 63, 2019
6P9C
DownloadVisualize
BU of 6p9c by Molmil
OXA-48 carbapanemase, doripenem complex
分子名称: (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, CADMIUM ION, ...
著者Smith, C.A, Vakulenko, S.B.
登録日2019-06-10
公開日2019-08-07
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.
Antimicrob.Agents Chemother., 63, 2019
6P53
DownloadVisualize
BU of 6p53 by Molmil
Crystal structure of the transpeptidase domain of PBP2 from Neisseria gonorrhoeae in apo form
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6HB8
DownloadVisualize
BU of 6hb8 by Molmil
Crystal structure of OXA-517 beta-lactamase
分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, Beta-lactamase, ...
著者Raczynska, J.E, Dabos, L, Zavala, A, Retailleau, P, Iorga, B, Jaskolski, M, Naas, T.
登録日2018-08-09
公開日2019-08-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Genetic, biochemical and structural characterization of OXA-517, an OXA-48-like extended-spectrum cephalosporins and carbapenems-hydrolyzing beta-lactamase
To Be Published
6HZI
DownloadVisualize
BU of 6hzi by Molmil
Apo structure of TP domain from Burkholderia pseudomallei penicillin-binding protein 3
分子名称: Peptidoglycan D,D-transpeptidase FtsI
著者Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
登録日2018-10-23
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Apo structure of TP domain from Burkholderia pseudomallei penicillin-binding protein 3
To Be Published
6HZO
DownloadVisualize
BU of 6hzo by Molmil
Apo structure of TP domain from Haemophilus influenzae Penicillin-Binding Protein 3
分子名称: FtsI
著者Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
登録日2018-10-23
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6HZQ
DownloadVisualize
BU of 6hzq by Molmil
Apo structure of TP domain from Escherichia coli Penicillin-Binding Protein 3
分子名称: Peptidoglycan D,D-transpeptidase FtsI
著者Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
登録日2018-10-23
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6GOA
DownloadVisualize
BU of 6goa by Molmil
Structural basis for OXA-48 dimerization - R189A mutant
分子名称: Beta-lactamase, CHLORIDE ION
著者Lund, B.A, Thomassen, A.M, Leiros, H.K.S.
登録日2018-06-01
公開日2018-07-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
6I1I
DownloadVisualize
BU of 6i1i by Molmil
Crystal structure of TP domain from Escherichia coli penicillin-binding protein 3 in complex with penicillin
分子名称: Peptidoglycan D,D-transpeptidase FtsI,Peptidoglycan D,D-transpeptidase FtsI, Piperacillin (Open Form)
著者Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
登録日2018-10-28
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6HOO
DownloadVisualize
BU of 6hoo by Molmil
Crystal Structure of Rationally Designed OXA-48loop18 beta-lactamase
分子名称: Beta-lactamase,OXA-48loop18,Beta-lactamase, FLUORIDE ION, GLYCEROL, ...
著者Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
登録日2018-09-17
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Substrate Specificity of OXA-48 after beta 5-beta 6 Loop Replacement.
Acs Infect Dis., 6, 2020
6HUH
DownloadVisualize
BU of 6huh by Molmil
CRYSTAL STRUCTURE OF OXA-427 class D BETA-LACTAMASE
分子名称: Beta-lactamase, SULFATE ION
著者Zavala, A, Retailleau, P, Bogaerts, P, Glupczynski, Y, Naas, T, Iorga, B.
登録日2018-10-08
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献CRYSTAL STRUCTURE OF CMY-OXA-427-HisTag BETA-LACTAMASE
To be published
6HZJ
DownloadVisualize
BU of 6hzj by Molmil
Apo structure of TP domain from clinical penicillin-resistant mutant Neisseria gonorrhoea strain 6140 Penicillin-Binding Protein 2 (PBP2)
分子名称: Probable peptidoglycan D,D-transpeptidase PenA
著者Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
登録日2018-10-23
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6I5D
DownloadVisualize
BU of 6i5d by Molmil
Crystal structure of an OXA-48 beta-lactamase synthetic mutant
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
登録日2018-11-13
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Substrate specificity of an OXA-48 beta-lactamase synthetic mutant
To be published

221716

件を2024-06-26に公開中

PDB statisticsPDBj update infoContact PDBjnumon