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PDB: 595 件

5XTD
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BU of 5xtd by Molmil
Cryo-EM structure of human respiratory complex I
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-19
公開日2017-08-30
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTI
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BU of 5xti by Molmil
Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-19
公開日2017-09-13
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (17.4 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
分子名称: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
登録日2020-05-04
公開日2020-10-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
5XTB
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BU of 5xtb by Molmil
Cryo-EM structure of human respiratory complex I matrix arm
分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-18
公開日2017-08-30
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
6ZKA
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BU of 6zka by Molmil
Membrane domain of open complex I during turnover
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKP
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BU of 6zkp by Molmil
Native complex I, open1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKD
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BU of 6zkd by Molmil
Complex I during turnover, open1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKT
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BU of 6zkt by Molmil
Deactive complex I, open2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKF
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BU of 6zkf by Molmil
Complex I during turnover, open3
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-14
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKU
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BU of 6zku by Molmil
Deactive complex I, open3
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
5WGB
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BU of 5wgb by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-13
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
7PD3
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BU of 7pd3 by Molmil
Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and MALSU1.L0R8F8.mt-ACP
分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Chandrasekaran, V, Desai, N, Burton, N.O, Yang, H, Price, J, Miska, E.A, Ramakrishnan, V.
登録日2021-08-04
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Visualizing formation of the active site in the mitochondrial ribosome.
Elife, 10, 2021
8ESW
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BU of 8esw by Molmil
Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Padavannil, A, Letts, J.A.
登録日2022-10-15
公開日2023-03-29
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8ESZ
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BU of 8esz by Molmil
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
分子名称: (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Padavannil, A, Letts, J.A.
登録日2022-10-15
公開日2023-03-29
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8EYI
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BU of 8eyi by Molmil
Atomic model of the core modifying region of human fatty acid synthase
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8EYK
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BU of 8eyk by Molmil
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
7PUA
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BU of 7pua by Molmil
Middle assembly intermediate of the Trypanosoma brucei mitoribosomal small subunit
分子名称: 30S Ribosomal protein S17, putative, 30S ribosomal protein S8, ...
著者Lenarcic, T, Leibundgut, M, Saurer, M, Ramrath, D.J.F, Fluegel, T, Boehringer, D, Ban, N.
登録日2021-09-29
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PSA
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BU of 7psa by Molmil
The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms
分子名称: (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Grba, D, Hirst, J.
登録日2021-09-22
公開日2022-04-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J.Biol.Chem., 298, 2022
7PO4
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BU of 7po4 by Molmil
Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP)
分子名称: 16SrRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
登録日2021-09-08
公開日2022-06-15
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
8IN9
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BU of 8in9 by Molmil
The structure of the GfsA KSQ-AT didomain in complex with the GfsA ACP domain
分子名称: N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase
著者Chisuga, T, Murakami, S, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2023-03-09
公開日2023-05-31
最終更新日2023-06-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase.
Acs Chem.Biol., 18, 2023
7QSD
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BU of 7qsd by Molmil
Bovine complex I in the active state at 3.1 A
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
著者Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
登録日2022-01-13
公開日2022-03-02
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7QH6
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BU of 7qh6 by Molmil
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1
分子名称: 16S ribosomal RNA, 39S ribosomal protein L13, mitochondrial, ...
著者Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M.
登録日2021-12-10
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit.
Nat Commun, 13, 2022
8GKC
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BU of 8gkc by Molmil
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640 - C2 refinement
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2023-03-17
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8I8D
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BU of 8i8d by Molmil
Acyl-ACP synthetase structure bound to MC7-ACP
分子名称: 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ...
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2023-02-03
公開日2024-02-07
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Acyl-ACP synthetase structure bound to MC7-ACP
To Be Published
8I8E
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BU of 8i8e by Molmil
Acyl-ACP synthetase structure bound to C18:1-ACP
分子名称: 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ...
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2023-02-04
公開日2024-02-07
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Acyl-ACP synthetase structure bound to C18:1-ACP
To Be Published

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件を2024-07-10に公開中

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