7QSD

Bovine complex I in the active state at 3.1 A

Summary for 7QSD

• Entry DOI: 10.2210/pdb7qsd/pdb
• EMDB information: 14127
• Descriptor: NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (56 entities in total)
• Functional Keywords: complex i, oxidoreductase
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 45
• Total formula weight: 1071016.18

Authors

Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Hirst, J. (deposition date: 2022-01-13, release date: 2022-03-02, Last modification date: 2023-03-08)

• Primary citation: Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Pollak, M.N.,Hirst, J.; Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.; Science, 379:351-357, 2023; PubMed: 36701435; DOI: 10.1126/science.ade3332

Experimental method

ELECTRON MICROSCOPY (3.1 Å)