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PDB: 73 件

4V1D
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Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.
分子名称: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ...
著者Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B.
登録日2014-09-25
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.
J.Biol.Chem., 291, 2016
2SN3
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STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, SCORPION NEUROTOXIN (VARIANT 3)
著者Zhao, B, Carson, M, Ealick, S.E, Bugg, C.E.
登録日1992-02-20
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of scorpion toxin variant-3 at 1.2 A resolution.
J.Mol.Biol., 227, 1992
1FH3
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NMR STRUCTURES OF LQH III ALPHA-LIKE SCORPION TOXIN FROM LEIURUS QUINQUESTRIATUS CORRESPONDING TO THE MAJOR CONFORMER IN SOLUTION
分子名称: LQH III ALPHA-LIKE TOXIN
著者Krimm, I, Trivelli, X, Lancelin, J.M.
登録日2000-07-31
公開日2000-08-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A Cis-trans Isomerism of a Non-prolyl Peptide Bond in Lqh III Alpha-like Scorpion Toxin Revealed by Solution NMR
To be Published
5MOU
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NMR spatial structure of scorpion alpha-like toxin BeM9
分子名称: Alpha-mammal toxin BeM9
著者Mineev, K.S, Kuldushev, N.A, Berkut, A.A, Grishin, E.V, Vassilevski, A.A, Arseniev, A.S.
登録日2016-12-14
公開日2018-01-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels.
Proteins, 86, 2018
4AEI
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Crystal structure of the AaHII-Fab4C1 complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALPHA-MAMMAL TOXIN AAH2, CHLORIDE ION, ...
著者Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P.
登録日2012-01-10
公開日2012-03-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
8BO0
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Solution structure of Lqq4 toxin from Leiurus quinquestriatus quinquestriatus
分子名称: Alpha-toxin Lqq4
著者Mineev, K.S, Motov, V.V, Vassilevski, A.A, Chernykh, M.A, Kuzmenkov, A.I.
登録日2022-11-14
公開日2023-09-20
最終更新日2023-10-04
実験手法SOLUTION NMR
主引用文献A scorpion toxin affecting sodium channels shows double cis-trans isomerism.
Febs Lett., 597, 2023
6THI
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Solution structure of MeuNaTxalpha-1 toxin from Mesobuthus Eupeus
分子名称: Sodium channel neurotoxin MeuNaTxalpha-1
著者Mineev, K.S, Kuzmenkov, A.I, Khusainov, G.A, Arseniev, A.S, Vassilevski, A.A.
登録日2019-11-20
公開日2020-12-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of MeuNaTx alpha-1 toxin from scorpion venom highlights the importance of the nest motif.
Proteins, 2021
5CY0
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Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography
分子名称: GLYCEROL, Ts3 Toxin
著者Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B.
登録日2015-07-29
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
Angew.Chem.Int.Ed.Engl., 55, 2016
6VXW
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NMR solution structure of natural scorpion toxin Cl13
分子名称: Beta-toxin Cl13
著者del Rio Portilla, F, Delepierre, M, Lopez Giraldo, A.E.
登録日2020-02-24
公開日2020-07-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus.
Toxicon, 184, 2020
1VNA
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PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING
分子名称: NEUROTOXIN
著者Lee, W, Krishna, N.R.
登録日1993-10-26
公開日1994-01-31
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochemistry, 33, 1994
1VNB
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PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING
分子名称: NEUROTOXIN
著者Lee, W, Krishna, N.R.
登録日1993-10-26
公開日1994-01-31
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochemistry, 33, 1994
4HHF
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Crystal Structure of chemically synthesized scorpion alpha-toxin OD1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1
著者Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T.
登録日2012-10-09
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
4KYP
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Beta-Scorpion Toxin folded in the periplasm of E.coli
分子名称: Beta-insect excitatory toxin Bj-xtrIT, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
著者O'Reilly, A.O, Cole, A.R, Lopes, J.L, Lampert, A, Wallace, B.A.
登録日2013-05-29
公開日2014-02-12
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
2YEO
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A39L mutation of scorpion toxin lqh-alpha-it
分子名称: 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ...
著者Frolow, F, Kahn, R, Gurevitz, M.
登録日2011-03-28
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
2YC1
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Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
分子名称: BETA-MAMMAL TOXIN CN2, GLYCEROL, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
著者Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
登録日2011-03-10
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
J.Biol.Chem., 286, 2011
2YBR
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Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
分子名称: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
著者Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
登録日2011-03-09
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
J.Biol.Chem., 286, 2011
2E0H
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Solution Structure of BmKalphaIT01, an alpha-insect toxin from the Venom of the Chinese Scorpion Buthus martensi Karsch
分子名称: Alpha-neurotoxin TX12
著者Tong, X.T, Chen, X, Wu, H.M.
登録日2006-10-08
公開日2007-10-16
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution Structure of BmKalphaIT01, an alpha-Insect Toxin from the Venom of the Chinese Scorpion Buthus martensii Karsch
Biochemistry, 46, 2007
2ASC
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Scorpion toxin LQH-alpha-IT
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ...
著者Kahn, R, Karbat, I, Gurevitz, M, Frolow, F.
登録日2005-08-23
公開日2006-09-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
2B3C
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SOLUTION STRUCTURE OF A BETA-NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING
分子名称: PROTEIN (NEUROTOXIN CSE-I)
著者Jablonsky, M.J, Jackson, P.L, Trent, J.O, Watt, D.D, Krishna, N.R.
登録日1998-12-09
公開日1998-12-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochem.Biophys.Res.Commun., 254, 1999
1PE4
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SOLUTION STRUCTURE OF TOXIN CN12 FROM CENTRUROIDES NOXIUS ALFA SCORPION TOXIN ACTING ON SODIUM CHANNELS. NMR STRUCTURE
分子名称: Neurotoxin Cn11
著者Del Rio-Portilla, F, Hernandez-Marin, E, Pimienta, G, Coronas, F.V, Zamudio, F.Z, Rodrguez de la Vega, R.C, Wanke, E, Possani, L.D.
登録日2003-05-21
公開日2004-05-25
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
Eur.J.Biochem., 271, 2004
1NRB
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SOLUTION STRUCTURE OF AN OLD WORLD-LIKE NEUROTOXIN FROM THE VENOM OF THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING
分子名称: NEUROTOXIN V, CSE-V
著者Jablonsky, M.J, Krishna, N.R.
登録日1995-01-03
公開日1995-02-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of an Old World-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing.
J.Mol.Biol., 248, 1995
1NH5
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AUTOMATIC ASSIGNMENT OF NMR DATA AND DETERMINATION OF THE PROTEIN STRUCTURE OF A NEW WORLD SCORPION NEUROTOXIN USING NOAH/DIAMOD
分子名称: Neurotoxin 5
著者Xu, Y, Jablonsky, M.J, Jackson, P.L, Krishna, N.R, Braun, W.
登録日2002-12-18
公開日2003-01-07
最終更新日2018-01-24
実験手法SOLUTION NMR
主引用文献Automatic assignment of NOESY Cross peaks and determination of the protein structure of a new world scorpion neurotoxin Using NOAH/DIAMOD
J.Magn.Reson., 148, 2001
1NRA
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SOLUTION STRUCTURE OF AN OLD WORLD-LIKE NEUROTOXIN FROM THE VENOM OF THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING
分子名称: NEUROTOXIN V, CSE-V
著者Jablonsky, M.J, Krishna, N.R.
登録日1995-01-03
公開日1995-02-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of an Old World-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing.
J.Mol.Biol., 248, 1995
1OMY
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Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch
分子名称: ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION
著者Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M.
登録日2003-02-26
公開日2003-09-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
1NPI
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Tityus Serrulatus Neurotoxin (Ts1) at atomic resolution
分子名称: PHOSPHATE ION, Toxin VII
著者Pinheiro, C.B, Marangoni, S, Toyama, M.H, Polikarpov, I.
登録日2003-01-17
公開日2003-02-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels.
Acta Crystallogr.,Sect.D, 59, 2003

 

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