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PDB: 189 件
1HQF
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE
分子名称: ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
1HQX
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R308K ARGINASE VARIANT
分子名称: ARGINASE, MANGANESE (II) ION
著者Lavulo, L.T, Sossong Jr, T.M, Brigham-Burke, M.R, Doyle, M.L, Cox, J.D, Christianson, D.W, Ash, D.E.
登録日2000-12-20
公開日2001-06-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Subunit-subunit interactions in trimeric arginase. Generation of active monomers by mutation of a single amino acid.
J.Biol.Chem., 276, 2001
1HQ5
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE
分子名称: ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W.
登録日2000-12-14
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum.
Biochemistry, 40, 2001
1HQH
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE
分子名称: ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
6VSS
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Arginase from Medicago truncatula
分子名称: Arginase, MANGANESE (II) ION
著者Sekula, B.
登録日2020-02-11
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci, 11, 2020
1XFK
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1.8A crystal structure of formiminoglutamase from Vibrio cholerae O1 biovar eltor str. N16961
分子名称: Formimidoylglutamase
著者Wu, R, Zhang, R, Shonda, C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-09-14
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.8A crystal structure of formiminoglutamas from Vibrio cholerae O1 biovar eltor str. N16961
To be Published
2AEB
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Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2005-07-21
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A0M
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Arginase superfamily protein from Trypanosoma cruzi
分子名称: ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
著者Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-06-16
公開日2005-07-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
1P8S
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
3E8Z
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X-ray structure of rat arginase I-N130A mutant: the unliganded complex
分子名称: Arginase-1, MANGANESE (II) ION
著者Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
登録日2008-08-20
公開日2008-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E9B
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X-ray structure of rat arginase I-T135A mutant: the complex with BEC
分子名称: Arginase-1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
登録日2008-08-21
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E8Q
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X-ray structure of rat arginase I-T135A: the unliganded complex
分子名称: Arginase-1, MANGANESE (II) ION
著者Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2008-08-20
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6K
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X-ray structure of Human Arginase I: the mutant D183A in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-08-15
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6V
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X-ray structure of human arginase I-D183N mutant: the complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-08-16
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
1PQ3
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Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
分子名称: Arginase II, mitochondrial precursor, CHLORIDE ION, ...
著者Cama, E, Colleluori, D.M, Emig, F.A, Shin, H, Kim, S.W, Kim, N.N, Traish, A.M, Ash, D.E, Christianson, D.W.
登録日2003-06-17
公開日2003-08-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
Biochemistry, 42, 2003
1P8Q
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Cluster of Arginase I.
分子名称: Arginase 1, GLYCEROL, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
1P8P
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
7K4I
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Human Arginase 1 in complex with compound 06.
分子名称: 3-[(1~{S},2~{S},5~{R})-2-carboxy-6-thia-3-azabicyclo[3.2.0]heptan-1-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2020-09-15
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7K4J
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Human Arginase 1 in complex with compound 51.
分子名称: 3-[(1~{S},2~{S},5~{R})-2-carboxy-3,6-diazabicyclo[3.2.0]heptan-1-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2020-09-15
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7K4H
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Human Arginase 1 in complex with compound 04.
分子名称: 3-[(1~{R},5~{S},8~{R})-5-carboxy-2,6-diazabicyclo[3.2.1]octan-8-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2020-09-15
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7K4K
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Human Arginase 1 in complex with compound 52.
分子名称: 3-[(3~{a}~{S},4~{S},6~{a}~{R})-4-carboxy-2,3,4,5,6,6~{a}-hexahydro-1~{H}-pyrrolo[2,3-c]pyrrol-3~{a}-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2020-09-15
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7K4G
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Human Arginase 1 in complex with compound 01.
分子名称: 3-[(2~{S},3~{R})-2-carboxypyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2020-09-15
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
3CEV
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ARGINASE FROM BACILLUS CALDEVELOX, COMPLEXED WITH L-ARGININE
分子名称: ARGININE, MANGANESE (II) ION, PROTEIN (ARGINASE)
著者Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
登録日1999-03-15
公開日1999-04-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
1P8M
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I.
Biochemistry, 42, 2003
1P8R
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, CHLORIDE ION, MANGANESE (II) ION, ...
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003

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