6V7C
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![BU of 6v7c by Molmil](/molmil-images/mine/6v7c) | Human Arginase1 Complexed with Bicyclic Inhibitor Compound 3 | 分子名称: | Arginase-1, MANGANESE (II) ION, {3-[(3aR,4S,5S,6aR)-5-azaniumyl-5-carboxyoctahydrocyclopenta[c]pyrrol-2-ium-4-yl]propyl}(trihydroxy)borate(1-) | 著者 | Palte, R.L. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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6V7D
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![BU of 6v7d by Molmil](/molmil-images/mine/6v7d) | Human Arginase1 Complexed with Bicyclic Inhibitor Compound 10 | 分子名称: | Arginase-1, MANGANESE (II) ION, {3-[(3aR,4R,5S,6aR)-4-azaniumyl-4-carboxyoctahydrocyclopenta[b]pyrrol-1-ium-5-yl]propyl}(trihydroxy)borate(1-) | 著者 | Palte, R.L, Lesburg, C.A. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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6V7E
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![BU of 6v7e by Molmil](/molmil-images/mine/6v7e) | Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12 | 分子名称: | 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | 著者 | Palte, R.L. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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6VSS
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![BU of 6vss by Molmil](/molmil-images/mine/6vss) | Arginase from Medicago truncatula | 分子名称: | Arginase, MANGANESE (II) ION | 著者 | Sekula, B. | 登録日 | 2020-02-11 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases. Front Plant Sci, 11, 2020
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6VST
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1GQ7
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![BU of 1gq7 by Molmil](/molmil-images/mine/1gq7) | PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS | 分子名称: | MANGANESE (II) ION, PROCLAVAMINATE AMIDINO HYDROLASE | 著者 | Elkins, J.M, Clifton, I.J, Hernandez, H, Robinson, C.V, Schofield, C.J, Hewitson, K.S. | 登録日 | 2001-11-20 | 公開日 | 2002-06-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis. Biochem. J., 366, 2002
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6VSU
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![BU of 6vsu by Molmil](/molmil-images/mine/6vsu) | |
1GQ6
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![BU of 1gq6 by Molmil](/molmil-images/mine/1gq6) | PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS | 分子名称: | MANGANESE (II) ION, PROCLAVAMINATE AMIDINO HYDROLASE | 著者 | Elkins, J.M, Clifton, I.J, Hernandez, H, Robinson, C.V, Schofield, C.J, Hewitson, K.S. | 登録日 | 2001-11-20 | 公開日 | 2002-06-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Oligomeric Structure of Proclavaminic Acid Amidino Hydrolase: Evolution of a Hydrolytic Enzyme in Clavulanic Acid Biosynthesis Biochem.J., 366, 2002
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1HQF
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![BU of 1hqf by Molmil](/molmil-images/mine/1hqf) | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE | 分子名称: | ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE | 著者 | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | 登録日 | 2000-12-16 | 公開日 | 2001-04-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1HQG
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![BU of 1hqg by Molmil](/molmil-images/mine/1hqg) | CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA | 分子名称: | ARGINASE 1, L-ornithine, MANGANESE (II) ION, ... | 著者 | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | 登録日 | 2000-12-16 | 公開日 | 2001-04-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1HQX
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![BU of 1hqx by Molmil](/molmil-images/mine/1hqx) | R308K ARGINASE VARIANT | 分子名称: | ARGINASE, MANGANESE (II) ION | 著者 | Lavulo, L.T, Sossong Jr, T.M, Brigham-Burke, M.R, Doyle, M.L, Cox, J.D, Christianson, D.W, Ash, D.E. | 登録日 | 2000-12-20 | 公開日 | 2001-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Subunit-subunit interactions in trimeric arginase. Generation of active monomers by mutation of a single amino acid. J.Biol.Chem., 276, 2001
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1HQ5
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![BU of 1hq5 by Molmil](/molmil-images/mine/1hq5) | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE | 分子名称: | ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | 著者 | Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W. | 登録日 | 2000-12-14 | 公開日 | 2001-04-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry, 40, 2001
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1HQH
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![BU of 1hqh by Molmil](/molmil-images/mine/1hqh) | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE | 分子名称: | ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE | 著者 | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | 登録日 | 2000-12-16 | 公開日 | 2001-04-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1P8S
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![BU of 1p8s by Molmil](/molmil-images/mine/1p8s) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8M
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![BU of 1p8m by Molmil](/molmil-images/mine/1p8m) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I. Biochemistry, 42, 2003
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1P8R
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![BU of 1p8r by Molmil](/molmil-images/mine/1p8r) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8Q
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![BU of 1p8q by Molmil](/molmil-images/mine/1p8q) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Cluster of Arginase I. | 分子名称: | Arginase 1, GLYCEROL, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8O
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![BU of 1p8o by Molmil](/molmil-images/mine/1p8o) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8N
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![BU of 1p8n by Molmil](/molmil-images/mine/1p8n) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, GLYCEROL, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8P
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![BU of 1p8p by Molmil](/molmil-images/mine/1p8p) | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2003-05-07 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1PQ3
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![BU of 1pq3 by Molmil](/molmil-images/mine/1pq3) | Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal | 分子名称: | Arginase II, mitochondrial precursor, CHLORIDE ION, ... | 著者 | Cama, E, Colleluori, D.M, Emig, F.A, Shin, H, Kim, S.W, Kim, N.N, Traish, A.M, Ash, D.E, Christianson, D.W. | 登録日 | 2003-06-17 | 公開日 | 2003-08-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal Biochemistry, 42, 2003
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3E8Q
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![BU of 3e8q by Molmil](/molmil-images/mine/3e8q) | X-ray structure of rat arginase I-T135A: the unliganded complex | 分子名称: | Arginase-1, MANGANESE (II) ION | 著者 | Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W. | 登録日 | 2008-08-20 | 公開日 | 2008-12-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Probing the specificity determinants of amino acid recognition by arginase. Biochemistry, 48, 2009
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3E6K
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3E6V
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3DJ8
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![BU of 3dj8 by Molmil](/molmil-images/mine/3dj8) | |