1HQX

R308K ARGINASE VARIANT

Summary for 1HQX

Related1RLA
DescriptorARGINASE, MANGANESE (II) ION (3 entities in total)
Functional Keywordsbinuclear manganese cluster, mutagenesis, arginase, subunit-subunit interactions, hydrolase
Biological sourceRattus norvegicus (Norway rat)
Total number of polymer chains3
Total molecular weight105302.87
Authors
Lavulo, L.T.,Sossong Jr., T.M.,Brigham-Burke, M.R.,Doyle, M.L.,Cox, J.D.,Christianson, D.W.,Ash, D.E. (deposition date: 2000-12-20, release date: 2001-06-06, Last modification date: 2019-10-23)
Primary citation
Lavulo, L.T.,Sossong Jr., T.M.,Brigham-Burke, M.R.,Doyle, M.L.,Cox, J.D.,Christianson, D.W.,Ash, D.E.
Subunit-subunit interactions in trimeric arginase. Generation of active monomers by mutation of a single amino acid.
J.Biol.Chem., 276:14242-14248, 2001
PubMed: 11278703 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M010575200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers403.6%9.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
168889
PDB entries from 2020-09-16