3E6V
X-ray structure of human arginase I-D183N mutant: the complex with ABH
Summary for 3E6V
| Entry DOI | 10.2210/pdb3e6v/pdb |
| Related | 2AEB 3E6K |
| Descriptor | Arginase-1, MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (4 entities in total) |
| Functional Keywords | amino acid recognition, mutant, amino group recognition, alternative splicing, arginine metabolism, cytoplasm, disease mutation, hydrolase, manganese, metal-binding, phosphoprotein, polymorphism, urea cycle |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm: P05089 |
| Total number of polymer chains | 2 |
| Total formula weight | 70161.54 |
| Authors | Di Costanzo, L.,Christianson, D.W. (deposition date: 2008-08-16, release date: 2008-12-02, Last modification date: 2023-08-30) |
| Primary citation | Shishova, E.Y.,Di Costanzo, L.,Emig, F.A.,Ash, D.E.,Christianson, D.W. Probing the specificity determinants of amino acid recognition by arginase. Biochemistry, 48:121-131, 2009 Cited by PubMed: 19093830DOI: 10.1021/bi801911v PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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