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PDB: 62 件

2QQM
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Crystal Structure of the a2b1b2 Domains from Human Neuropilin-1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQK
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Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Heavy Chain, Antibody Light Chain, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
1NT0
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Crystal structure of the CUB1-EGF-CUB2 region of MASP2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Feinberg, H, Uitdehaag, J.C.M, Davies, J.M, Wallis, R, Drickamer, K, Weis, W.I.
登録日2003-01-28
公開日2003-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Embo J., 22, 2003
2QQL
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Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
分子名称: Antibody Heavy Chain, Antibody Light Chain, Neuropilin-2
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
1NZI
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BU of 1nzi by Molmil
Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s
分子名称: CALCIUM ION, Complement C1s component, MAGNESIUM ION
著者Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C.
登録日2003-02-18
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement
J.Biol.Chem., 278, 2003
6F1H
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C1rC1s complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R.
登録日2017-11-22
公開日2018-01-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4LMF
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C1s CUB1-EGF-CUB2
分子名称: CALCIUM ION, Complement C1s subcomponent heavy chain, SODIUM ION
著者Wallis, R, Venkatraman Girija, U, Moody, P.C.E, Marshall, J.E.
登録日2013-07-10
公開日2013-08-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.921 Å)
主引用文献Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6F1C
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C1rC1s complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1r subcomponent, ...
著者Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R.
登録日2017-11-21
公開日2018-01-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F39
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C1r homodimer CUB1-EGF-CUB2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1r subcomponent, ...
著者Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R.
登録日2017-11-28
公開日2018-01-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (5.801 Å)
主引用文献Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5CIS
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BU of 5cis by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2
著者Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
登録日2015-07-13
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
5CKM
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BU of 5ckm by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2
著者Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
登録日2015-07-15
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
5CKQ
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CUB1-EGF-CUB2 domains of rat MASP-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine protease 1, ...
著者Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
登録日2015-07-15
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.704 Å)
主引用文献Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
5CKN
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BU of 5ckn by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
分子名称: CALCIUM ION, Mannan-binding lectin serine peptidase 2
著者Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
登録日2015-07-15
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
4LOR
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BU of 4lor by Molmil
C1s CUB1-EGF-CUB2 in complex with a collagen-like peptide from C1q
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1s subcomponent heavy chain, ...
著者Wallis, R, Venkatraman Girija, U, Moody, P.C.E, Marshall, J.E.
登録日2013-07-13
公開日2013-08-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
7BZT
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BU of 7bzt by Molmil
Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ...
著者Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J.
登録日2020-04-28
公開日2020-07-22
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1.
Proc.Natl.Acad.Sci.USA, 117, 2020
4AQB
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BU of 4aqb by Molmil
MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44
分子名称: CALCIUM ION, MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Skjoedt, M.O, Roversi, P, Hummelshoj, T, Palarasah, Y, Johnson, S, Lea, S.M, Garred, P.
登録日2012-04-16
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1).
J.Biol.Chem., 287, 2012
6V55
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BU of 6v55 by Molmil
Full extracellular region of zebrafish Gpr126/Adgrg6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G-protein coupled receptor G6, CALCIUM ION
著者Leon, K, Arac, D.
登録日2019-12-03
公開日2020-01-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis for adhesion G protein-coupled receptor Gpr126 function.
Nat Commun, 11, 2020
6SNW
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BU of 6snw by Molmil
Structure of Coxsackievirus A10 complexed with its receptor KREMEN1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP3, ...
著者Zhao, Y, Zhou, D, Ni, T, Karia, D, Kotecha, A, Wang, X, Rao, Z, Jones, E.Y, Fry, E.E, Ren, J, Stuart, D.I.
登録日2019-08-27
公開日2020-01-15
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10.
Nat Commun, 11, 2020
8H3U
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Inhibitor-bound EP, polyA model
分子名称: Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者Ding, Z.Y, Huang, H.J.
登録日2022-10-09
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
8H3S
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Substrate-bound EP, polyA model
分子名称: Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain, Serine protease 1
著者Ding, Z.Y, Huang, H.J.
登録日2022-10-09
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
7WQZ
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BU of 7wqz by Molmil
Structure of Active-mutEP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日2022-01-26
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
7WQW
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Structure of Active-EP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日2022-01-26
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
7WR7
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BU of 7wr7 by Molmil
Structure of Inhibited-EP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, Enteropeptidase catalytic light chain, ...
著者Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日2022-01-26
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
7WQX
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Structure of Inactive-EP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase
著者Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日2022-01-26
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.
Nat Commun, 13, 2022
4LOS
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BU of 4los by Molmil
C1s CUB2-CCP1
分子名称: CALCIUM ION, Complement C1s subcomponent heavy chain
著者Wallis, R, Venkatraman Girija, U, Moody, P.C.E, Marshall, J.E, Gingras, A.R.
登録日2013-07-13
公開日2013-08-07
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Proc.Natl.Acad.Sci.USA, 110, 2013

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