5CKQ

CUB1-EGF-CUB2 domains of rat MASP-1

Summary for 5CKQ

Entry DOI	10.2210/pdb5ckq/pdb
Descriptor	Mannan-binding lectin serine protease 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
Functional Keywords	cub1-egf-cub2, serine protease, lectin pathway, complement, hydrolase
Biological source	Rattus norvegicus (Norway Rat)
Cellular location	Secreted : Q8CHN8
Total number of polymer chains	1
Total formula weight	32475.64
Authors	Nan, R.,Furze, C.M.,Wright, D.W.,Gor, J.,Wallis, R.,Perkins, S.J. (deposition date: 2015-07-15, release date: 2017-01-18, Last modification date: 2024-01-10)
Primary citation	Nan, R.,Furze, C.M.,Wright, D.W.,Gor, J.,Wallis, R.,Perkins, S.J. Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation. Structure, 25:364-375, 2017 Cited by PubMed: 28111019 DOI: 10.1016/j.str.2016.12.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.704 Å)

Structure validation