4LOS

C1s CUB2-CCP1

Summary for 4LOS

• Entry DOI: 10.2210/pdb4los/pdb
• Related: 4LMF 4LOS 4LOT
• Descriptor: Complement C1s subcomponent heavy chain, CALCIUM ION (3 entities in total)
• Functional Keywords: cub domain, ccp domain, complement c1s, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20760.34

Authors

Wallis, R.,Venkatraman Girija, U.,Moody, P.C.E.,Marshall, J.E.,Gingras, A.R. (deposition date: 2013-07-13, release date: 2013-08-07, Last modification date: 2013-09-04)

• Primary citation: Venkatraman Girija, U.,Gingras, A.R.,Marshall, J.E.,Panchal, R.,Sheikh, M.A.,Gal, P.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.,Wallis, R.; Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.; Proc.Natl.Acad.Sci.USA, 110:13916-13920, 2013; PubMed: 23922389; DOI: 10.1073/pnas.1311113110

Experimental method

X-RAY DIFFRACTION (1.996 Å)